| Trial ID: | L0526 |
| Source ID: | NCT00806481
|
| Associated Drug: |
Sevelamer Carbonate
|
| Title: |
Effects of Phosphate Binding With Sevelamer in Stage 3 Chronic Kidney Disease
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Kidney Failure, Chronic|Cardiovascular Diseases
|
| Interventions: |
DRUG: Sevelamer carbonate|DRUG: Placebo
|
| Outcome Measures: |
Primary: Change in left ventricular mass, 36 weeks | Secondary: Aortic compliance as measured by cardiac magnetic resonance imaging, 36 weeks|Arterial stiffness as measured by pulse wave velocity and pulse wave analysis, 36 weeks|Arterial elastance as measured by echocardiography, 36 weeks|Left ventricular systolic and diastolic elastance measured by echocardiography, 36 weeks|Bone density on dual-energy x-ray absorptiometry scanning, 36 weeks
|
| Sponsor/Collaborators: |
Sponsor: University Hospital Birmingham NHS Foundation Trust | Collaborators: Genzyme, a Sanofi Company
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
120
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2009-02
|
| Completion Date: |
2011-10
|
| Results First Posted: |
|
| Last Update Posted: |
2011-11-23
|
| Locations: |
University Hospital Birmingham NHS Foundation Trust, Birmingham, West Midlands, B15 2TH, United Kingdom
|
| URL: |
https://clinicaltrials.gov/show/NCT00806481
|
