| Trial ID: | L5284 |
| Source ID: | NCT02655770
|
| Associated Drug: |
Liraglutide
|
| Title: |
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus Type 2|Diastolic Dysfunction|Cardiac MRI|Myocardial Perfusion
|
| Interventions: |
DRUG: Liraglutide|DRUG: Placebo
|
| Outcome Measures: |
Primary: Change in diastolic properties as assessed by CMR., LA passive emptying fraction (%) (before and after glycopyrolate), Measured in week 18 and compared to baseline.|Change in diastolic properties as assessed by CMR., LV peak filling rate (ml/s) (before and after glycopyrolate), Measured in week 18 and compared to baseline. | Secondary: MRI indices of myocardial perfusion, Measured in week 18 and compared to baseline.|Echocardiographic indices of diastolic dysfunction, Measured in week 18 and compared to baseline.
|
| Sponsor/Collaborators: |
Sponsor: Rigshospitalet, Denmark | Collaborators: Slagelse Hospital|Novo Nordisk A/S
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
40
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2016-02
|
| Completion Date: |
2019-12
|
| Results First Posted: |
|
| Last Update Posted: |
2021-01-14
|
| Locations: |
The department of cardiology, Rigshospitalet Denmark, Copenhagen Ø, 210, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT02655770
|
