| Trial ID: | L5302 |
| Source ID: | NCT00404599
|
| Associated Drug: |
Atrorvastatin 10mg
|
| Title: |
Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.
|
| Acronym: |
SOS
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus|Hypertension
|
| Interventions: |
DRUG: atrorvastatin 10mg|DRUG: simvastatin 40mg
|
| Outcome Measures: |
Primary: Reduction in oxLDL levels, july 2009 | Secondary: Reduction in plasma malondialdehydes and urine isoprostanes, july 2009|Reduction in plasma endothelial function parameters such as soluble Vascular Adhesion Molecule (sVCAM) and von Willebrand factor, july 2009
|
| Sponsor/Collaborators: |
Sponsor: Amsterdam UMC, location VUmc
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
60
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
|
| Start Date: |
2007-02
|
| Completion Date: |
2009-07
|
| Results First Posted: |
|
| Last Update Posted: |
2008-06-10
|
| Locations: |
VU University Medical Center, Amsterdam, 1007 MB, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT00404599
|
