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Clinical Trial Details

Trial ID: L5701
Source ID: NCT03087032
Associated Drug: Liraglutide
Title: Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
Acronym: LiraGooD
Status: RECRUITING
Study Results: NO
Results:
Conditions: Type 2 Diabetes Patients|Overweight and Obesity|Hyperglycaemia (Diabetic)
Interventions: DRUG: Liraglutide|DRUG: insulin glargine
Outcome Measures: Primary: the proportion of patients with HbA1c < 7.0% without experiencing hypoglycemia and without weight gain,with a superiority margin of 3%, the net difference in the proportion of patients with HbA1c \< 7.0% without experiencing hypoglycemia and without weight gain is more than 3%, 24 weeks | Secondary: the proportion of patients with hypoglycemia, the proportion of patients with hypoglycemia, 24 weeks|changes in HbA1c, changes in HbA1c, 24 weeks|changes from baseline in FPG(mmol/L), changes from baseline in FPG(mmol/L), 24 weeks|changes in body weight ( kilograms), changes in body weight( kilograms), 24 weeks|changes in prandial insulin dosage (per kilogram), changes in prandial insulin dosage (per kilogram), 24 weeks|changes in visceral as assessed by dual x-ray absorptiometry (DXA), changes in visceral as assessed by dual x-ray absorptiometry (DXA), 24 weeks|number of participants with abnormal laboratory values and/or adverse events that are related to treatment, number of participants with abnormal laboratory values and/or adverse events, 24 weeks|changes in serum c-peptide level, changes in serum c-peptide level, 24 weeks|changes in systolic pressure, changes in systolic pressure, 24 weeks|changes in diastolic pressure, changes in diastolic pressure, 24 weeks|changes in serum lipid profile, changes in serum lipid profile, 24 weeks
Sponsor/Collaborators: Sponsor: The First Affiliated Hospital of Xiamen University
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE4
Enrollment: 164
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2019-01-10
Completion Date: 2025-02-10
Results First Posted:
Last Update Posted: 2025-01-13
Locations: The first afilliated hospital of Xiamen university, Xiamen, Fujian, 361003, China
URL: https://clinicaltrials.gov/show/NCT03087032