| Trial ID: | L5751 |
| Source ID: | NCT01285232
|
| Associated Drug: |
Anakinra
|
| Title: |
The Effect of Anakinra on Insulin Secretion
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Glucose Intolerance|Impaired Insulin Secretion|Diabetes Mellitus Type 2
|
| Interventions: |
DRUG: Anakinra
|
| Outcome Measures: |
Primary: To determine the effect of anakinra on insulin secretion, as derived from hyperglycemic clamps ., after 4 weeks of treatment with anakinra | Secondary: To determine the effect on anakinra on insulin sensitivity., Oral glucose tolerance test, after 4 week treatment of anakinra|Effects of anakinra on fat cell morphology and gene expression, Fatbiopsy, after 4 weeks of treatment with anakinra
|
| Sponsor/Collaborators: |
Sponsor: Radboud University Medical Center
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
16
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
|
| Start Date: |
2011-01
|
| Completion Date: |
2012-12
|
| Results First Posted: |
|
| Last Update Posted: |
2012-03-26
|
| Locations: |
Radboud University Nijmegen Medical Centre, Nijmegen, 6500HB, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT01285232
|
