| Trial ID: | L5755 |
| Source ID: | NCT04419337
|
| Associated Drug: |
Metformin Plus Pioglitazone Plus An Sglt2 Inhibitor
|
| Title: |
Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus|Stroke
|
| Interventions: |
DRUG: Metformin plus Pioglitazone plus an SGLT2 inhibitor
|
| Outcome Measures: |
Primary: HbA1C, blood test to evaluate glycemic control, 6 months from baseline in active vs control arms | Secondary: UACR, to evaluate microalbuminuria, 6 months from randomization in active vs control arms|hs-CRP, to evaluate hs-CRP in active vs control arms, 6 months from randomization|NT-proBNP, to evaluate NT-proBNP in active vs control arms, 6 months from randomization|insulin resistance, Insulin resistance will be evaluated by Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), 6 months from randomization
|
| Sponsor/Collaborators: |
Sponsor: Chang Gung Memorial Hospital | Collaborators: National Taiwan University Hospital|Chiayi Christian Hospital|Tainan Sin-lau Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
200
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2019-09-15
|
| Completion Date: |
2024-01-31
|
| Results First Posted: |
|
| Last Update Posted: |
2023-03-30
|
| Locations: |
Chang Gung Memorial Hospital, Chiayi Branch, Chiayi City, 613, Taiwan
|
| URL: |
https://clinicaltrials.gov/show/NCT04419337
|
