| Trial ID: | L5857 |
| Source ID: | NCT00849576
|
| Associated Drug: |
Regular Human Insulin
|
| Title: |
Effect of Treatment With Insulin VIAjectTM Compared to Regular Human Insulin and Insulin Lispro on Mealtime Blood Vessel Stress in Patients With Type 2 Diabetes Mellitus.
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Regular Human Insulin|DRUG: Insulin Lispro|DRUG: Insulin VIAject™ (75%)|DRUG: Insulin VIAject™ (90%)
|
| Outcome Measures: |
Primary: Postprandial time course of Asymmetric dimethyl arginine (ADMA) after injection of insulin VIAjectTM compared with regular human insulin and insulin lispro., 0 - 240 minutes | Secondary: The secondary objectives are to evaluate the postprandial time course of arterial elasticity (pulse wave analysis; PWA), blood glucose, insulin, intact proinsulin, nitrotyrosine, glucagon, ICAM-1, VCAM, E-selectin., 0 - 240 minutes
|
| Sponsor/Collaborators: |
Sponsor: Biodel
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE3
|
| Enrollment: |
15
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2008-04
|
| Completion Date: |
2008-08
|
| Results First Posted: |
|
| Last Update Posted: |
2015-08-03
|
| Locations: |
IKFE, Parcusstrasse 8, Mainz, 55116, Germany
|
| URL: |
https://clinicaltrials.gov/show/NCT00849576
|
