Clinical Trial Details
| Trial ID: | L5890 |
| Source ID: | NCT01664676 |
| Associated Drug: | Liraglutide |
| Title: | Effects of Liraglutide on Kidney Function in Type 2 Diabetic Patients |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Type 2 Diabetes Mellitus |
| Interventions: | DRUG: Liraglutide|DRUG: Placebo-liraglutide |
| Outcome Measures: | Primary: Glomerular Filtration Rate (51Cr-EDTA plasma clearance), 10-15 hours post-dose | Secondary: Renal Blood Flow (functional magnetic resonance imaging), 15 hours post-dose|Renal electrolyte clearance, Sodium, potassium, calcium, lithium and osmotically active substances., 10-15 hours post-dose|Excretion of kidney injury markers, Albumin, NGAL, KIM-1, angiotensinogen and 8-OHdG., 0-10 hours and 10-15 hours post-dose|Plasma concentrations of various hormones, Angiotensin II, renin, aldosterone, atrial natriuretic peptide, catecholamines., 10-15 hours post-dose |
| Sponsor/Collaborators: | Sponsor: University of Aarhus | Collaborators: Novo Nordisk A/S|University of Copenhagen |
| Gender: | MALE |
| Age: | ADULT |
| Phases: | PHASE4 |
| Enrollment: | 11 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT |
| Start Date: | 2012-12 |
| Completion Date: | 2014-02 |
| Results First Posted: | |
| Last Update Posted: | 2014-02-28 |
| Locations: | Aarhus University Hospital, Department of Endocrinology and Diabetes, Aarhus, 8000, Denmark |
| URL: | https://clinicaltrials.gov/show/NCT01664676 |
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