| Outcome Measures: |
Primary: UACR percent change at Week 24, Percentage change in urine albumin-to-creatinine ratio (UACR) after 24 weeks compared to baseline (%), Week 24 | Secondary: UACR change at Week 24 (%), Change in urine albumin-to-creatinine ratio (UACR) after 24 weeks compared to baseline (%), Week 24|UACR change at Week 12, Change in urine albumin-to-creatinine ratio (UACR) after 12 weeks compared to baseline (mg/g, Week 12|HbA1c change at Week 24, Change in glycated hemoglobin after 24 weeks compared to baseline, Week 24|HbA1c change at Week 12, Change in glycated hemoglobin after 12 weeks compared to baseline, Week 12|HbA1c less than 6.5% at Week 24, proportion of parcipitants having glycated hemoglobin less than 6.5% after 24 weeks, Week 24|HbA1c less than 6.5% at Week 12, proportion of participants having glycated hemoglobin less than 6.5% after 12 weeks, Week 12|HbA1c less than 7.0% at Week 24, proportion of participants having glycated hemoglobin less than 7.0% after 24weeks, Week 24|HbA1c less than 7.0% at Week 12, proportion of participants having glycated hemoglobin less than 7.0% after 12 weeks, Week 12|NAG (N-acetyl-β-D-glucosaminidase) change at Week 24, Change in NAG (N-acetyl-β-D-glucosaminidase) after 24 weeks compared to baseline (U/L), Week 24|NAG (N-acetyl-β-D-glucosaminidase) change at Week 12, Change in NAG (N-acetyl-β-D-glucosaminidase) after 12 weeks compared to baseline (U/L), Week 12|Cystatin-C change at Week 24, Change in urinary Cystatin-C after 24 weeks compared to baseline (mg/L), Week 24|Cystatin-C change at Week 12, Change in urinary Cystatin-C after 12 weeks compared to baseline (mg/L), Week 12|Nephrin change at Week 24, Change in Nephrin after 24 weeks compared to baseline (ug/g cr), Week 24|Nephrin change at Week 12, Change in Nephrin after 12 weeks compared to baseline (ug/g cr), Week 12|Glycated albumin change at Week 24, Change in Glycated albumin after 24 weeks compared to baseline (%), Week 24|Glycated albumin change at Week 12, Change in Glycated albumin after 12 weeks compared to baseline (%), Week 12|eGFR at Week 24, Change in estimated glomerular filtration rate based on Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) method after 24 weeks compared to baseline (mL/min), Week 24|eGFR change at Week 12, Change in estimated glomerular filtration rate based on Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) method after 12 weeks compared to baseline (mL/min), Week 12
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