| Trial ID: | L5962 |
| Source ID: | NCT00419835
|
| Associated Drug: |
Enalapril
|
| Title: |
Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Macroalbuminuric Diabetic Nephropathy
|
| Interventions: |
DRUG: enalapril|DRUG: losartan
|
| Outcome Measures: |
Primary: effect of treatment on proteinuria after 8 months of follow-up | Secondary: effect of treatment on urinary inflammatory biomarkers after 8 months of follow-up|incidence of hyperkalemia
|
| Sponsor/Collaborators: |
Sponsor: University of Sao Paulo | Collaborators: Fundação de Amparo à Pesquisa do Estado de São Paulo
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
80
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2005-05
|
| Completion Date: |
2007-09
|
| Results First Posted: |
|
| Last Update Posted: |
2011-08-04
|
| Locations: |
Nephrology Department, Sao Paulo University Medical School, Sao Paulo, 05403-010, Brazil
|
| URL: |
https://clinicaltrials.gov/show/NCT00419835
|
