| Trial ID: | L0611 |
| Source ID: | NCT03142529
|
| Associated Drug: |
Colon Lotion
|
| Title: |
Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney Disease
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Failure|End-Stage Kidney Disease
|
| Interventions: |
DRUG: colon lotion
|
| Outcome Measures: |
Primary: Change of glomerular filtration rate index, measuring the level of urea nitrogen，blood urea nitrogen,serum creatinine, serum cystatin C, blood and urineβ2-microglobulin. calculating the creatinine clearance rate., the first day before intervention and the eleventh day|Change of intestinal flora, measuring serum endotoxin and investigating the differences of intestinal flora between control group and experience group，as well as the differences between before colonic dialysis and after colonic dialysis., the first day before intervention and the eleventh day | Secondary: Change of serum electrolyte changes, measuring serum contents of sodium，potassium and phosphorus., the first day before intervention and the eleventh day|Change of related inflammatory index, measuring hs-C reactive protein(hs-CRP),interleukin 1β(IL-1β)，IL-6，tumor necrosis factor α(TNF-α) in serum., the first day before intervention and the eleventh day|Change of renal fibrosis index, measuring platelet derived growth factor (PDGF) secretion and serum transforming growth factor β(TGF-β)., the first day before intervention and the eleventh day
|
| Sponsor/Collaborators: |
Sponsor: Pang Peng | Collaborators: Guangdong Provincial Hospital of Traditional Chinese Medicine
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE1|PHASE2
|
| Enrollment: |
20
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2017-05-15
|
| Completion Date: |
2018-10-15
|
| Results First Posted: |
|
| Last Update Posted: |
2018-05-30
|
| Locations: |
Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, 510006, China
|
| URL: |
https://clinicaltrials.gov/show/NCT03142529
|
