| Trial ID: | L6180 |
| Source ID: | NCT02129985
|
| Associated Drug: |
Exenatide
|
| Title: |
Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy
|
| Acronym: |
T2DMRS
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Exenatide|DRUG: Metformin
|
| Outcome Measures: |
Primary: time to glycaemic remission, time of glycaemic remission at 1 year after exenatide sequential therapy followed by a short-term insulin intensive treatment, up to 1 year|remission rate of type 2 diabetes at a year., remission rate of type 2 diabetes after short-term intensive insulin and exenatide sequencial therapy, up to 1 year | Secondary: the beta cell function change, the beta cell function change expressed by the ratio of proinsulin to insulin in fasting state and HOMA beta,the ratio of Glucose change to insulin change between at 30min and 0min time point of OGTT, 1 year | Other: HbA1C level at every 3 months during the whole study, HbA1C level at every 3 months during the whole study, 1 year|mean glucose level during the follow without drug intervention, mean glucose level during the follow without drug intervention, 1 year|number of hypoglycemia and severe hypoglycemia during the study, number of hypoglycemia and severe hypoglycemia during the study, up to 1 year
|
| Sponsor/Collaborators: |
Sponsor: xiaolong zhao | Collaborators: Shanghai Zhongshan Hospital|The third people's Hospital Affiliated to Shanghai Jiao Tong University|Second Affiliated Hospital of Soochow University|The First Hospital of Guiyang Medical college|Fuling Central Hospital of Chongqing City|Taizhou Hospital|Shanghai Pudong New Area Gongli Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
100
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2014-02
|
| Completion Date: |
2015-09
|
| Results First Posted: |
|
| Last Update Posted: |
2014-05-02
|
| Locations: |
Xiaolong Zhao, Jingan, Shanghai, 20041, China
|
| URL: |
https://clinicaltrials.gov/show/NCT02129985
|
