| Trial ID: | L6192 |
| Source ID: | NCT02310009
|
| Associated Drug: |
Anakinra (An)
|
| Title: |
IL-1RA, Acute Exercise, and Beta-cell Function
|
| Acronym: |
ANEX
|
| Status: |
WITHDRAWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Anakinra (AN)|BEHAVIORAL: Exercise (EX)|BEHAVIORAL: Control (CON)
|
| Outcome Measures: |
Primary: Beta-cell function, A hyperglycemic clamp will be performed combined with glucagon-like peptide(GLP)-1 infusion and arginine injection. The primary outcome is the insulin secretory response to glucose, GLP-1, and arginine., 1 day after intervention | Secondary: Glucose disposition, The glucose disposal rate during hyperglycemic clamp, 1 day after intervention
|
| Sponsor/Collaborators: |
Sponsor: Rigshospitalet, Denmark
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
0
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2014-12
|
| Completion Date: |
2015-07-30
|
| Results First Posted: |
|
| Last Update Posted: |
2017-02-13
|
| Locations: |
Rigshospitalet, Copenhagen, Denmark
|
| URL: |
https://clinicaltrials.gov/show/NCT02310009
|
