| Trial ID: | L6301 |
| Source ID: | NCT01779609
|
| Associated Drug: |
Bosentan
|
| Title: |
ET-blockade and Exercise-induced Vascular Adaptations in T2DM
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Bosentan|DRUG: Placebo|BEHAVIORAL: Exercise
|
| Outcome Measures: |
Primary: Flow mediated dilation, 8 weeks | Secondary: Conduit Artery Dilator Capacity, 8 weeks|Intima-Media Thickness, 8 weeks|Maximal Oxygen Uptake, 8 weeks
|
| Sponsor/Collaborators: |
Sponsor: Radboud University Medical Center | Collaborators: Actelion
|
| Gender: |
MALE
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
19
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
|
| Start Date: |
2010-04
|
| Completion Date: |
2013-12
|
| Results First Posted: |
|
| Last Update Posted: |
2016-05-05
|
| Locations: |
Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, 6525 EX, Netherlands
|
| URL: |
https://clinicaltrials.gov/show/NCT01779609
|
