| Trial ID: | L0637 |
| Source ID: | NCT00808795
|
| Associated Drug: |
N-Acetylcysteine
|
| Title: |
Efficacy of N-Acetylcysteine in Prevention of Post-Catheterization Contrast-Induced Nephropathy in Diabetic Patients With Chronic Kidney Disease
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Radiocontrast-Induced Nephropathy|Chronic Kidney Disease|Diabetes Mellitus
|
| Interventions: |
DRUG: N-acetylcysteine|DRUG: Placebo
|
| Outcome Measures: |
Primary: Incidence of CIN, defined as increase in serum creatinine concentration>=0.5mg/dL(44.2micromol/L) or >=25% above baseline., 48 hours after exposure to contrast medium | Secondary: Change in serum creatinine, 48 hours after exposure to contrast medium|Change in serum urea nitrogen, 48 hours after exposure to contrast medium|Change in Glomerular filtration rate(GFR), 48 hours after exposure to contrast medium
|
| Sponsor/Collaborators: |
Sponsor: Tehran University of Medical Sciences
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE3
|
| Enrollment: |
90
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
|
| Start Date: |
2006-04
|
| Completion Date: |
2006-10
|
| Results First Posted: |
|
| Last Update Posted: |
2008-12-16
|
| Locations: |
Tehran Heart center, Tehran, 1411713138, Iran, Islamic Republic of
|
| URL: |
https://clinicaltrials.gov/show/NCT00808795
|
