| Trial ID: | L6406 |
| Source ID: | NCT00762671
|
| Associated Drug: |
Ebselen
|
| Title: |
Signaling Mechanisms and Vascular Function in Patients With Diabetes Mellitus
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
|
| Interventions: |
DRUG: Ebselen|DRUG: Placebo
|
| Outcome Measures: |
Primary: Endothelium-dependent and endothelium-independent vasodilation of peripheral resistance and conduit vessels will be studied in diabetic (type 1 and 2) and healthy subjects two weeks following randomization to the ebselen or placebo., one testing visit every 4 weeks |
|
| Sponsor/Collaborators: |
Sponsor: Brigham and Women's Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2|PHASE3
|
| Enrollment: |
60
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
1999-05
|
| Completion Date: |
2007-10
|
| Results First Posted: |
|
| Last Update Posted: |
2008-09-30
|
| Locations: |
Brigham and Women's Hosptial, Boston, Massachusetts, 02115, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT00762671
|
