| Outcome Measures: |
Primary: HbA1c, Changes in HbA1c compared to baseline at week 24, Baseline, week 24 | Secondary: HbA1c, Changes in HbA1c compared to baseline at week 16, Baseline, week 16|Fasting blood glucose, Changes in Fasting blood glucose compared to baseline at week 16,week 24, Baseline, week 16，week 24|2-hour postprandial blood glucose, Changes in 2-hour postprandial blood glucose compared to baseline at week 24, Baseline, week 24|fasting insulin, Changes in fasting insulin compared to baseline at week 24, Baseline, week 24|fasting glucagon, Changes in fasting glucagon compared to baseline at week 24, Baseline, week 24|active Glucagon-like peptide-1（GLP-1） level, Changes in active Glucagon-like peptide-1（GLP-1） level compared to baseline at 24, Baseline, week 24|The percentage of HbA1c<6.5% and HbA1c<7%, The percentage of HbA1c\<6.5% and HbA1c\<7% at week 24, week 24|body weight, Changes in body weight（Kg）compared to baseline at week 24, Baseline, week 24|Body Mass Index, Changes in Body Mass Index （kg/m\^2）compared to baseline at week 24, Baseline, week 24
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