| Outcome Measures: |
Primary: changes from baseline HbA1c at week 25, baseline (Visit 2) and week 25 (visit 6) | Secondary: Responder Rate at week 25, HbA1c \<7% , HbA1c \<6.5%, week 25 (visit 6)|Changes of HbA1c at each visit, values of parameters at the corresponding visit - values of parameters at visit 2(baseline), baseline(visit 2), week 7(visit 3), week 13(visit 4), week 19(visit 5), week 25(visit 6)|Changes of FPG at each visit, values of parameters at the corresponding visit - values of parameters at visit 2(baseline), baseline(visit 2), week 7(visit 3), week 13(visit 4), week 19(visit 5), week 25(visit 6)|Changes of Fasting serum C-peptide at week 25, baseline (Visit 2) and week 25 (visit 6)|Changes of HOMA-IR at week 25, baseline (Visit 2) and week 25 (visit 6)|Changes of HOMA-β at week 25, baseline (Visit 2) and week 25 (visit 6) | Other: Changes of Total Cholesterol at week 25, baseline (Visit 2) and week 25 (visit 6)|Changes of cardiovascular disease parameter at week 25, hsCRP, baseline (Visit 2) and week 25 (visit 6)|Changes of body weight at each visit, values of parameters at the corresponding visit - values of parameters at visit 2(baseline), baseline(visit 2), week 7(visit 3), week 13(visit 4), week 19(visit 5), week 25(visit 6)|Changes of waist circumference at each visit, values of parameters at the corresponding visit - values of parameters at visit 2(baseline), baseline(visit 2), week 7(visit 3), week 13(visit 4), week 19(visit 5), week 25(visit 6)|Changes of total daily dose at each visit, values of parameters at the corresponding visit - values of parameters at visit 2(baseline), visit 2, visit 3, visit 4, visit 5, visit 6|Changes of LDL-C at week 25, baseline (Visit 2) and week 25 (visit 6)|Changes of HDL-C at week 25, baseline (Visit 2) and week 25 (visit 6)|Changes of Triglyceride at week 25, baseline (Visit 2) and week 25 (visit 6)
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