Clinical Trial Details
| Trial ID: | L6709 |
| Source ID: | NCT00817271 |
| Associated Drug: | Azd1656 |
| Title: | To Evaluate the Response to Glucagon During Hypoglycemia |
| Acronym: | |
| Status: | COMPLETED |
| Study Results: | NO |
| Results: | |
| Conditions: | Type 2 Diabetes |
| Interventions: | DRUG: AZD1656|DRUG: Glucagon |
| Outcome Measures: | Primary: P-Glucose levels, Repeated sampling during the 24 hour period on day 5 and 8 | Secondary: Safety and tolerability (AE, BP, pulse, plasma glucose, laboratory variables, weight and ECG), Frequent measurements during the study period|Pharmacokinetic variables (Area under the plasma conc-time curve from time 0 to 24 hours post dose (AUC0-24), maximum plasma conc(Cmax), time to reach maximum plasma conc(tmax), terminal elimination half-life and apparent oral clearance, Repeated sampling during the 24 hour period on day 5 and 8|Pharmacodynamics (P-Glucose, S-Insulin and S-C-peptide), Repeated sampling during the 24 hour period on day 5 and 8 |
| Sponsor/Collaborators: | Sponsor: AstraZeneca |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | PHASE1 |
| Enrollment: | 8 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT |
| Start Date: | 2009-02 |
| Completion Date: | 2009-04 |
| Results First Posted: | |
| Last Update Posted: | 2009-05-07 |
| Locations: | Research Site, Chula Vista, California, United States |
| URL: | https://clinicaltrials.gov/show/NCT00817271 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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