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Clinical Trial Details

Trial ID: L0679
Source ID: NCT06830629
Associated Drug: Mze829
Title: A Phase 2 Study of MZE829 in Adults with APOL1 Kidney Disease
Acronym:
Status: RECRUITING
Study Results: NO
Results:
Conditions: Proteinuric Kidney Disease
Interventions: DRUG: MZE829
Outcome Measures: Primary: Safety and tolerability as assessed by incidence of adverse events (AEs), Day 1 to Week 12 | Secondary: Percent participants with ≥30% reduction from baseline in UACR at Week 12, Day 1 to Week 12|Geometric mean plasma drug concentrations, Day 1 to Week 12
Sponsor/Collaborators: Sponsor: Maze Therapeutics
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE2
Enrollment: 56
Study Type: INTERVENTIONAL
Study Designs: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2025-02-05
Completion Date: 2026-09
Results First Posted:
Last Update Posted: 2025-02-17
Locations: Apogee Clinical Research, Huntsville, Alabama, 35805, United States|Amicis Research Center, Fairfield, California, 94534, United States|Amicis Research Center, Granada Hills, California, 91344, United States|Amicis Research Center, Palmdale, California, 93551, United States|Amicis Research Center, Valencia, California, 91355, United States|Clinical Research of Brandon, LLC, Brandon, Florida, 33511, United States|Florida Kidney Physicians, Fort Lauderdale, Florida, 33316, United States|Florida Kidney Physicians, Jacksonville, Florida, 32250, United States|San Marcus Research Clinic, Inc., Miami Lakes, Florida, 33014, United States|Florida Kidney Physicians, Riverview, Florida, 33578, United States|Primeway Clinical Research Group, College Park, Georgia, 30349, United States|Research by Design, LLC, Chicago, Illinois, 60643, United States|Aa Mrc Mhs, Flint, Michigan, 48503, United States|St. Clair Nephrology Research, Shelby Township, Michigan, 48315, United States|Prime Health and Wellness, Fayette, Mississippi, 39069, United States|SKY Integrative Medical Center, Ridgeland, Mississippi, 39157, United States|AB Clinical Trials, Las Vegas, Nevada, 89119, United States|Carolina Kidney Associates, P.A., Greensboro, North Carolina, 27405, United States|Clinical Renal Associates, Upland, Pennsylvania, 19013, United States|CN Clinical Research, LLC, Spartanburg, South Carolina, 29306, United States|Renal Specialist, Houston, Texas, 77030, United States|Virginia Nephrology Group, Arlington, Virginia, 22205, United States
URL: https://clinicaltrials.gov/show/NCT06830629

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress