| Outcome Measures: |
Primary: IL6, Change of IL6 during exercise stimulation at baseline compared to change of IL6 during exercise stimulation at day 7 | Secondary: change of inflammatory markers (CRP, Tumor Necrosis Factor alpha, IL-1Ra), Change of inflammatory markers during exercise stimulation at baseline compared to change of inflammatory markers during exercise stimulation at day 7|Muscle soreness, Change in muscle soreness before and after exercise stimulation at baseline compared to change in muscle soreness before and after exercise stimulation at day 7|Activity induced Fatigue (ACTIF) Scale, Change in ACTIF before and after exercise stimulation at baseline compared to change in ACTIF before and after exercise stimulation at day 7|Depression, Change in depression during exercise stimulation at baseline compared to change in depression at day 7|Change of vascular function (CAVI, pulse wave velocity, AVR), Change in vascular function during exercise stimulation at baseline compared to change of vascular function at day 7|glucose metabolism, Change glucose metabolism during exercise stimulation at basleine compared to change in glucose metabolism during exercise stimulation at day 7|Cognition, Change in cognition during exercise stimulation at baseline compared to change in cognition at day 7|Motor strength, Change in motor strength during exercise stimulation at baseline compared to change in motor stength at day 7|Insulin, Change in insulin during exercise stimulation at baseline compared to change in insulin at day 7|Glucagon, Change in glucagon during exercise stimulation at baseline compared to change in glucagon at day 7|GLP-1, Change in GLP-1 during exercise stimulation at baseline compared to change in GLP-1 at day 7|Cortisol, Change in cortisol during exercise stimulation at baseline compared to change in cortisol at day 7|Creatinkinase, Change in creatinkinase during exercise stimulation at baseline compared to change in creatinkinase at day 7|Growth hormone, Change of growth hormone during exercise stimulation at baseline compared to change of growth hormone during exercise stimulation at day 7|Copeptin, Change of copeptin during exercise stimulation at baseline compared to change of copeptin during exercise stimulation at day 7
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