| Trial ID: | L7061 |
| Source ID: | NCT05556005
|
| Associated Drug: |
Trimetazidine Dihydrochloride
|
| Title: |
Efficacy of Trimetazidine in Diabetic Patients
|
| Acronym: |
|
| Status: |
UNKNOWN
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Diabetes Mellitus, Type 2|Diabetic Cardiomyopathies
|
| Interventions: |
DRUG: Trimetazidine Dihydrochloride|DRUG: Placebo
|
| Outcome Measures: |
Primary: Change from baseline Left ventricular functions at 3 months, assessed using echocardiographic and tissue doppler evaluation, at baseline and after three months of intervention | Secondary: Change from baseline Tumor necrosis factor alpha at 3 months, assessed using ELISA technique, at baseline and after three months of intervention|Change from baseline Transforming growth factor beta 1 at 3 months, assessed using ELISA technique, at baseline and after three months of intervention
|
| Sponsor/Collaborators: |
Sponsor: Ain Shams University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
60
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2022-09-18
|
| Completion Date: |
2023-09
|
| Results First Posted: |
|
| Last Update Posted: |
2022-09-27
|
| Locations: |
Ainshams university hospitals, Cairo, Egypt
|
| URL: |
https://clinicaltrials.gov/show/NCT05556005
|
