| Trial ID: | L7209 |
| Source ID: | NCT06132477
|
| Associated Drug: |
Glp-1 Receptor Agonist
|
| Title: |
Impact GLP-1 Agonists Following Bariatric
|
| Acronym: |
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| Status: |
RECRUITING
|
| Study Results: |
NO
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| Results: |
|
| Conditions: |
Morbid Obesity|Metabolic Syndrome|Diabetes Mellitus|Hypertension|Obstructive Sleep Apnea of Adult
|
| Interventions: |
DRUG: GLP-1 receptor agonist
|
| Outcome Measures: |
Primary: Effect of GLP1-RA on weight loss, To investigate the effects of GLP1-RAs on weight loss reflected as change in BMI (kg per meter sq) in patients undergoing metabolic surgery, 6 months|Effect of GLP1-RA on circulating bile acids and metabolites, Determine the impact of GLP1-RA on circulating bile acids and other metabolites, 6 months|Effector of GLP1-RA on gut microbiome diversity, To determine the impact of GLP1-RAs after bariatric surgery on changes in the gut microbiome, 6 months|Effect of GLP1-RA on satiety and hunger, To assess the impact of GLP-1 agonists on satiety and hunger in patients who undergo metabolic surgery. Scale will be a validated scoring system, "Daily Eats Questionnaire," with scores ranging from 0-10, with a 0 indicating no hunger, and 10 indicating extreme hunger, 6 months|Effect of GLP1-RA on Glycemic control, HGBA1C levels will be measured at 3 and 6 months after surgery to determine if HGBA1C drops more in patients maintained on GLP1-RA, 6 months |
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| Sponsor/Collaborators: |
Sponsor: University of Missouri-Columbia | Collaborators: American Society for Metabolic and Bariatric Surgery
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| Gender: |
ALL
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| Age: |
ADULT, OLDER_ADULT
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| Phases: |
PHASE4
|
| Enrollment: |
150
|
| Study Type: |
INTERVENTIONAL
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| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
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| Start Date: |
2024-02-01
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| Completion Date: |
2028-07
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| Results First Posted: |
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| Last Update Posted: |
2024-09-20
|
| Locations: |
University of Missouri Hospital, Columbia, Missouri, 65201, United States
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| URL: |
https://clinicaltrials.gov/show/NCT06132477
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