Logo 1 Logo 2

Clinical Trial Details

Trial ID: L7276
Source ID: NCT02192853
Associated Drug: Sitagliptin
Title: Correlation Between Plasma- and Endothelial DPP-4 Activity
Acronym:
Status: COMPLETED
Study Results: NO
Results:
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin|DRUG: Placebo
Outcome Measures: Primary: Correlation between the total and intact GLP-1 hormone during different doses of sitagliptin measured as total area under the curve (tAUC), GLP.1 total and GLP-1 intact will be calculated based on blood samples at time points: -40,-30,-20,-10,0,10,20,30,40,50,60,75,90,105,120,150,180,240,300,360 on all days | Secondary: Differences in serum-/plasma concentrations of GLP-1 measured as total Area under the curve (tAUC), GLP-1 will be measured at time points(minutes): -40,-30,-20,-10,0,10,20,30,40,50,60,75,90,105,120,150,180,240,300,360 on all days|Differences in glucose measured as total Area under the curve (tAUC), Glucose will be measured at time points(minutes): -40,-30,-20,-10,0,10,20,30,40,50,60,75,90,105,120,150,180,240,300,360 on all days|Differences in Insulin measured as total Area under the curve (tAUC), Insulin will be measured at time points(minutes): -40,-30,-20,-10,0,10,20,30,40,50,60,75,90,105,120,150,180,240,300,360 on all days
Sponsor/Collaborators: Sponsor: University Hospital, Gentofte, Copenhagen
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE4
Enrollment: 20
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Start Date: 2013-05
Completion Date: 2014-03
Results First Posted:
Last Update Posted: 2017-09-11
Locations: Diabetes Research Division, Department of Endocrinology, Gentofte Hospital, Hellerup, 2900, Denmark
URL: https://clinicaltrials.gov/show/NCT02192853