| Trial ID: | L7285 |
| Source ID: | NCT01349387
|
| Associated Drug: |
Metformin
|
| Title: |
Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing
|
| Acronym: |
METFORGENE
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 2 Diabetes
|
| Interventions: |
DRUG: Metformin
|
| Outcome Measures: |
Primary: Comparison of expression of isoforms A and B of the insulin receptor using quantitative RT PCR, comparison of the A isoform (without inclusion of exon 11) and B isoform (with inclusion of exon 11) ratio of the receptor in insulin, during the first period (without metformin) and the second period (with metformin), inclusion (baseline), 30th days and 60th days |
|
| Sponsor/Collaborators: |
Sponsor: Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
25
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2011-05
|
| Completion Date: |
2012-01
|
| Results First Posted: |
|
| Last Update Posted: |
2012-02-09
|
| Locations: |
Centre Hospitalier Sud Francilien, Corbeil Essonnes, 91106, France
|
| URL: |
https://clinicaltrials.gov/show/NCT01349387
|
