CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Clinical Trial Details

Trial ID:	L7291
Source ID:	NCT00331851
Associated Drug:	Liraglutide
Title:	Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Acronym:	LEAD-5
Status:	COMPLETED
Study Results:	NO
Results:
Conditions:	Diabetes\|Diabetes Mellitus, Type 2
Interventions:	DRUG: liraglutide\|DRUG: insulin glargine\|DRUG: metformin\|DRUG: glimepiride
Outcome Measures:	Primary: HbA1c, after 26 weeks of treatment \| Secondary: body weight\|Safety and tolerability\|Beta-cell function\|Glycaemic control
Sponsor/Collaborators:	Sponsor: Novo Nordisk A/S
Gender:	ALL
Age:	ADULT, OLDER_ADULT
Phases:	PHASE3
Enrollment:	584
Study Type:	INTERVENTIONAL
Study Designs:	Allocation: RANDOMIZED\|Intervention Model: PARALLEL\|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)\|Primary Purpose: TREATMENT
Start Date:	2006-05
Completion Date:	2007-04
Results First Posted:
Last Update Posted:	2017-01-26
Locations:	Novo Nordisk Investigational Site, Bahía Blanca, 8000, Argentina\|Novo Nordisk Investigational Site, Ciudad Autonoma de Bs As, C1405CWB, Argentina\|Novo Nordisk Investigational Site, Junín, 6000, Argentina\|Novo Nordisk Investigational Site, Mendoza, 5500, Argentina\|Novo Nordisk Investigational Site, Rosario, 2000, Argentina\|Novo Nordisk Investigational Site, Bregenz, A - 6900, Austria\|Novo Nordisk Investigational Site, Wien, 1010, Austria\|Novo Nordisk Investigational Site, Wien, 1030, Austria\|Novo Nordisk Investigational Site, Wien, 1120, Austria\|Novo Nordisk Investigational Site, Wien, 1130, Austria\|Novo Nordisk Investigational Site, Wien, 1230, Austria\|Novo Nordisk Investigational Site, Wien, A 1090, Austria\|Novo Nordisk Investigational Site, Curitiba, 80810-040, Brazil\|Novo Nordisk Investigational Site, Rio de Janeiro, 20211-340, Brazil\|Novo Nordisk Investigational Site, Rio de Janeiro, 21941-590, Brazil\|Novo Nordisk Investigational Site, San Paulo, 11060-001, Brazil\|Novo Nordisk Investigational Site, Sao Paulo, 80540-010, Brazil\|Novo Nordisk Investigational Site, São Paulo, 05403-000, Brazil\|Novo Nordisk Investigational Site, Esbjerg, 6700, Denmark\|Novo Nordisk Investigational Site, Gentofte, 2820, Denmark\|Novo Nordisk Investigational Site, Hellerup, 2900, Denmark\|Novo Nordisk Investigational Site, Hillerød, 3400, Denmark\|Novo Nordisk Investigational Site, Roskilde, 4000, Denmark\|Novo Nordisk Investigational Site, Slagelse, 4200, Denmark\|Novo Nordisk Investigational Site, Århus C, 8000, Denmark\|Novo Nordisk Investigational Site, Helsinki, 00250, Finland\|Novo Nordisk Investigational Site, Helsinki, 00260, Finland\|Novo Nordisk Investigational Site, Kuopio, 70210, Finland\|Novo Nordisk Investigational Site, Oulu, FI-90220, Finland\|Novo Nordisk Investigational Site, Turku, 20700, Finland\|Novo Nordisk Investigational Site, Belgrade, 11000, Former Serbia and Montenegro\|Novo Nordisk Investigational Site, Nis, 18000, Former Serbia and Montenegro\|Novo Nordisk Investigational Site, Besancon, 25030, France\|Novo Nordisk Investigational Site, Brest, 29200, France\|Novo Nordisk Investigational Site, Corbeil Essonnes, 91106, France\|Novo Nordisk Investigational Site, DIJON cedex, 21079, France\|Novo Nordisk Investigational Site, LA ROCHELLE cedex, 17019, France\|Novo Nordisk Investigational Site, Nanterre, 92014, France\|Novo Nordisk Investigational Site, Narbonne, 11108, France\|Novo Nordisk Investigational Site, NEVERS cedex, 58033, France\|Novo Nordisk Investigational Site, Venissieux, 69200, France\|Novo Nordisk Investigational Site, Hyderabad, Andhra Pradesh, 500034, India\|Novo Nordisk Investigational Site, Karnal, Haryana, 132001, India\|Novo Nordisk Investigational Site, Pune, Maharashtra, 411 037, India\|Novo Nordisk Investigational Site, Hyderabad, 600034, India\|Novo Nordisk Investigational Site, Patna, 800020, India\|Novo Nordisk Investigational Site, Bergamo, 24127, Italy\|Novo Nordisk Investigational Site, Bologna, 40133, Italy\|Novo Nordisk Investigational Site, Catania, 95124, Italy\|Novo Nordisk Investigational Site, Catanzaro, 88100, Italy\|Novo Nordisk Investigational Site, Chieri, 10023, Italy\|Novo Nordisk Investigational Site, Chieti Scalo, 66100, Italy\|Novo Nordisk Investigational Site, Messina, 98123, Italy\|Novo Nordisk Investigational Site, Padova, 35143, Italy\|Novo Nordisk Investigational Site, Parma, 43100, Italy\|Novo Nordisk Investigational Site, Siena, 53100, Italy\|Novo Nordisk Investigational Site, Almere, 1311RL, Netherlands\|Novo Nordisk Investigational Site, Den Haag, 2512 VA, Netherlands\|Novo Nordisk Investigational Site, Den Helder, 1782 GZ, Netherlands\|Novo Nordisk Investigational Site, Eindhoven, 5631 BM, Netherlands\|Novo Nordisk Investigational Site, Gouda, 2803HH, Netherlands\|Novo Nordisk Investigational Site, Maastricht, 6229 HX, Netherlands\|Novo Nordisk Investigational Site, Zevenaar, 6903 ZN, Netherlands\|Novo Nordisk Investigational Site, Zoetermeer, 2725 NA, Netherlands\|Novo Nordisk Investigational Site, Bergen, 5021, Norway\|Novo Nordisk Investigational Site, Gjettum, 1346, Norway\|Novo Nordisk Investigational Site, Jessheim, 2050, Norway\|Novo Nordisk Investigational Site, Nordbyhagen, 1474, Norway\|Novo Nordisk Investigational Site, Notodden, 3675, Norway\|Novo Nordisk Investigational Site, Sandvika, NO-1337, Norway\|Novo Nordisk Investigational Site, Skedsmokorset, NO-2020, Norway\|Novo Nordisk Investigational Site, Cebu City, 6000, Philippines\|Novo Nordisk Investigational Site, Manila, 1000, Philippines\|Novo Nordisk Investigational Site, Marikina City, 1810, Philippines\|Novo Nordisk Investigational Site, Pasig City, 1605, Philippines\|Novo Nordisk Investigational Site, Gdynia, 81-366, Poland\|Novo Nordisk Investigational Site, Katowice, 40-053, Poland\|Novo Nordisk Investigational Site, Opole, 45-418, Poland\|Novo Nordisk Investigational Site, Poznan, 60-821, Poland\|Novo Nordisk Investigational Site, Wroclaw, 50-127, Poland\|Novo Nordisk Investigational Site, Zabrze, 41-800, Poland\|Novo Nordisk Investigational Site, Moscow, 117036, Russian Federation\|Novo Nordisk Investigational Site, Moscow, 123448, Russian Federation\|Novo Nordisk Investigational Site, Moscow, 127644, Russian Federation\|Novo Nordisk Investigational Site, Banska Bystrica, 95717, Slovakia\|Novo Nordisk Investigational Site, Bratislava, 811 08, Slovakia\|Novo Nordisk Investigational Site, L'ubochna, 03491, Slovakia\|Novo Nordisk Investigational Site, Martin, 036 59, Slovakia\|Novo Nordisk Investigational Site, Nitra, 94 911, Slovakia\|Novo Nordisk Investigational Site, Zilina, 01001, Slovakia\|Novo Nordisk Investigational Site, Bloemfontein, Free State, 6850, South Africa\|Novo Nordisk Investigational Site, Pretoria, Gauteng, 0001, South Africa\|Novo Nordisk Investigational Site, Pretoria, Gauteng, 0181, South Africa\|Novo Nordisk Investigational Site, Worcester, Western Cape, 6850, South Africa\|Novo Nordisk Investigational Site, Baracaldo, 48903, Spain\|Novo Nordisk Investigational Site, Barcelona, 08035, Spain\|Novo Nordisk Investigational Site, Getafe, 28905, Spain\|Novo Nordisk Investigational Site, Málaga, 29009, Spain\|Novo Nordisk Investigational Site, Santiago de Compostela, 15706, Spain\|Novo Nordisk Investigational Site, Sevilla, 41014, Spain\|Novo Nordisk Investigational Site, Valencia, 46014, Spain\|Novo Nordisk Investigational Site, Valencia, 46015, Spain\|Novo Nordisk Investigational Site, Valencia, 46026, Spain\|Novo Nordisk Investigational Site, Valladolid, 47011, Spain\|Novo Nordisk Investigational Site, Ayr, KA6 6DX, United Kingdom\|Novo Nordisk Investigational Site, Bradford, BD9 6RJ, United Kingdom\|Novo Nordisk Investigational Site, Guildford, GU2 7XX, United Kingdom\|Novo Nordisk Investigational Site, Liverpool, L9 7AL, United Kingdom\|Novo Nordisk Investigational Site, Livingstone, EH54 6PP, United Kingdom\|Novo Nordisk Investigational Site, Llantrisant, CF72 8XR, United Kingdom\|Novo Nordisk Investigational Site, Manchester, M41 5SL, United Kingdom\|Novo Nordisk Investigational Site, Nottingham, NG7 2UH, United Kingdom\|Novo Nordisk Investigational Site, Salford, M6 8HD, United Kingdom\|Novo Nordisk Investigational Site, Sheffield, S5 7AU, United Kingdom\|Novo Nordisk Investigational Site, Swansea, SA6 6NL, United Kingdom\|Novo Nordisk Investigational Site, Watford, WD18 0HB, United Kingdom
URL:	https://clinicaltrials.gov/show/NCT00331851

Knowledge Graph
Associated Data

Drug ID	Drug Name	Type	DrugBank ID	Targets	Category	Latest Progress
D089	Metformin	small molecule	DB00331				Details

Clinical Trial Details

Summary

Knowledge Graph

Associated Data

Associated NAFLD Drugs (1)