| Trial ID: | L0732 |
| Source ID: | NCT00446251
|
| Associated Drug: |
Rituximab
|
| Title: |
Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT00446251/results
|
| Conditions: |
Kidney Failure, Chronic|Diabetic Nephropathies|Glomerulonephritis, IGA|Hypertension, Renal
|
| Interventions: |
DRUG: Rituximab|DRUG: Mycophenolate mofetil (MMF)
|
| Outcome Measures: |
Primary: The Number of Subjects Who Experience a Decrease in Their Panel of Reactive Antibodies (PRA) at 6 Months Post Rituximab Infusion., the number of subjects who experience a decrease in their Panel of Reactive Antibodies (PRA) at 6 months and 12 months post Rituximab infusion, Month 6 from start of study | Secondary: The Number of Subjects Who Experience a Change From Baseline in Their Panel of Reactive Antibody (PRA) Titers at 12 Months Post Rituximab Infusion., Month 12 from start of study|The Number of Subjects With a Negative Crossmatch at the Time of Transplant., Month 12 from start of study
|
| Sponsor/Collaborators: |
Sponsor: University of Washington | Collaborators: Genentech, Inc.
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
14
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2006-12
|
| Completion Date: |
2008-12
|
| Results First Posted: |
2010-03-29
|
| Last Update Posted: |
2010-04-06
|
| Locations: |
|
| URL: |
https://clinicaltrials.gov/show/NCT00446251
|
