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Clinical Trial Details

Trial ID: L0746
Source ID: NCT00680017
Associated Drug: Abt-335 Plus Rosuvastatin
Title: 30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney Disease
Acronym:
Status: COMPLETED
Study Results: YES
Results: https://ClinicalTrials.gov/show/NCT00680017/results
Conditions: Dyslipidemia|Kidney Disease
Interventions: DRUG: ABT-335 plus rosuvastatin|DRUG: Rosuvastatin
Outcome Measures: Primary: Median Percent Change in Triglycerides From Baseline to Week 8., Triglycerides were measured in milligrams/deciliter., Baseline to 8 weeks | Secondary: Mean Percent Change in High-Density Lipoprotein Cholesterol From Baseline to Week 8., High-density lipoprotein cholesterol (HDL-C) was measured in milligrams/deciliter (mg/dL)., Baseline to 8 weeks
Sponsor/Collaborators: Sponsor: AstraZeneca
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE3
Enrollment: 280
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Start Date: 2008-06
Completion Date: 2011-04
Results First Posted: 2012-07-16
Last Update Posted: 2012-10-03
Locations: Site Reference ID/Investigator# 22521, Birmingham, Alabama, 35242, United States|Site Reference ID/Investigator# 22478, Huntsville, Alabama, 35801, United States|Site Reference ID/Investigator# 8365, Madison, Alabama, 35758, United States|Site Reference ID/Investigator# 8416, Montgomery, Alabama, 36106-1111, United States|Site Reference ID/Investigator# 7869, Chula Vista, California, 91910, United States|Site Reference ID/Investigator# 8435, Fountain Valley, California, 92708, United States|Site Reference ID/Investigator# 22487, Lincoln, California, 95648, United States|Site Reference ID/Investigator# 22426, Long Beach, California, 90806, United States|Site Reference ID/Investigator# 8096, Los Angeles, California, 90048, United States|Site Reference ID/Investigator# 22962, Norwalk, California, 90650, United States|Site Reference ID/Investigator# 8311, Riverside, California, 92505, United States|Site Reference ID/Investigator# 22816, Sacramento, California, 95825, United States|Site Reference ID/Investigator# 8510, Simi Valley, California, 93065, United States|Site Reference ID/Investigator# 22821, West Hills, California, 91307, United States|Site Reference ID/Investigator# 7958, Arvada, Colorado, 80002, United States|Site Reference ID/Investigator# 15881, Denver, Colorado, 80230, United States|Site Reference ID/Investigator# 8399, Westminster, Colorado, 80031, United States|Site Reference ID/Investigator# 23224, Boynton Beach, Florida, 33472, United States|Site Reference ID/Investigator# 22474, Clearwater, Florida, 33756, United States|Site Reference ID/Investigator# 21803, Coral Springs, Florida, 33065, United States|Site Reference ID/Investigator# 22811, Daytona Beach, Florida, 32117, United States|Site Reference ID/Investigator# 27103, Hollywood, Florida, 33021, United States|Site Reference ID/Investigator# 8398, Hudson, Florida, 34667, United States|Site Reference ID/Investigator# 26723, Kissimmee, Florida, 34741, United States|Site Reference ID/Investigator# 37676, Kissimmee, Florida, 34759, United States|Site Reference ID/Investigator# 8231, Lauderdale Lakes, Florida, 33313, United States|Site Reference ID/Investigator# 22486, Longwood, Florida, 32779, United States|Site Reference ID/Investigator# 22520, New Port Richey, Florida, 34652, United States|Site Reference ID/Investigator# 8226, Orlando, Florida, 32804, United States|Site Reference ID/Investigator# 22477, Ormond Beach, Florida, 32174, United States|Site Reference ID/Investigator# 8386, Pembroke Pines, Florida, 33028, United States|Site Reference ID/Investigator# 22518, Plant City, Florida, 33563, United States|Site Reference ID/Investigator# 12882, Port Charlotte, Florida, 33952, United States|Site Reference ID/Investigator# 37675, St. Cloud, Florida, 34769, United States|Site Reference ID/Investigator# 8410, West Palm Beach, Florida, 33401, United States|Site Reference ID/Investigator# 21802, Winter Haven, Florida, 33880, United States|Site Reference ID/Investigator# 8136, Atlanta, Georgia, 30331, United States|Site Reference ID/Investigator# 23503, Dunwoody, Georgia, 30338, United States|Site Reference ID/Investigator# 7948, Macon, Georgia, 31217, United States|Site Reference ID/Investigator# 22819, Roswell, Georgia, 30076, United States|Site Reference ID/Investigator# 22813, Suwanee, Georgia, 30024, United States|Site Reference ID/Investigator# 27682, Chicago, Illinois, 60616, United States|Site Reference ID/Investigator# 8227, Peoria, Illinois, 61603, United States|Site Reference ID/Investigator# 13922, Mishawaka, Indiana, 46545-3519, United States|Site Reference ID/Investigator# 8094, Council Bluffs, Iowa, 51501, United States|Site Reference ID/Investigator# 22430, Iowa City, Iowa, 52242, United States|Site Reference ID/Investigator# 8093, Paducah, Kentucky, 42003, United States|Site Reference ID/Investigator# 38405, Baton Rouge, Louisiana, 70809, United States|Site Reference ID/Investigator# 8903, Shreveport, Louisiana, 71101, United States|Site Reference ID/Investigator# 21805, Auburn, Maine, 04210, United States|Site Reference ID/Investigator# 8092, Rockville, Maryland, 20852, United States|Site Reference ID/Investigator# 8225, Fall River, Massachusetts, 02720, United States|Site Reference ID/Investigator# 8407, Springfield, Massachusetts, 01107, United States|Site Reference ID/Investigator# 8415, Royal Oak, Michigan, 48073, United States|Site Reference ID/Investigator# 22222, Brooklyn Center, Minnesota, 55430, United States|Site Reference ID/Investigator# 8408, Olive Branch, Mississippi, 38654, United States|Site Reference ID/Investigator# 22703, Berlin, New Jersey, 08009, United States|Site Reference ID/Investigator# 22707, Elizabeth, New Jersey, 07202, United States|Site Reference ID/Investigator# 22702, Hillsborough, New Jersey, 08844, United States|Site Reference ID/Investigator# 8387, Flushing, New York, 11355, United States|Site Reference ID/Investigator# 8177, Great Neck, New York, 11021, United States|Site Reference ID/Investigator# 8146, Lake Success, New York, 11042, United States|Site Reference ID/Investigator# 22427, Williamsville, New York, 14221, United States|Site Reference ID/Investigator# 22481, Charlotte, North Carolina, 28262, United States|Site Reference ID/Investigator# 22708, Charlotte, North Carolina, 28277, United States|Site Reference ID/Investigator# 8434, Morehead City, North Carolina, 28557, United States|Site Reference ID/Investigator# 8417, Cincinnati, Ohio, 45267-0585, United States|Site Reference ID/Investigator# 8147, Columbus, Ohio, 43215, United States|Site Reference ID/Investigator# 22488, Mason, Ohio, 45040, United States|Site Reference ID/Investigator# 22479, Oklahoma City, Oklahoma, 73103, United States|Site Reference ID/Investigator# 23225, Oklahoma City, Oklahoma, 73112, United States|Site Reference ID/Investigator# 22482, Tulsa, Oklahoma, 74136, United States|Site Reference ID/Investigator# 8345, Bend, Oregon, 97701, United States|Site Reference ID/Investigator# 22704, Medford, Oregon, 97504, United States|Site Reference ID/Investigator# 8400, Portland, Oregon, 97210, United States|Site Reference ID/Investigator# 8411, Bethlehem, Pennsylvania, 18017, United States|Site Reference ID/Investigator# 8405, Carlisle, Pennsylvania, 17015, United States|Site Reference ID/Investigator# 22387, Duncansville, Pennsylvania, 16635, United States|Site Reference ID/Investigator# 22815, Jersey Shore, Pennsylvania, 17740, United States|Site Reference ID/Investigator# 12881, Johnstown, Pennsylvania, 15905, United States|Site Reference ID/Investigator# 22706, Perkasie, Pennsylvania, 18944, United States|Site Reference ID/Investigator# 8095, Philadelphia, Pennsylvania, 19107, United States|Site Reference ID/Investigator# 22705, Tipton, Pennsylvania, 16684, United States|Site Reference ID/Investigator# 22817, Warminster, Pennsylvania, 18974, United States|Site Reference ID/Investigator# 8098, Providence, Rhode Island, 02904, United States|Site Reference ID/Investigator# 22823, Charleston, South Carolina, 29412, United States|Site Reference ID/Investigator# 8364, Columbia, South Carolina, 29206, United States|Site Reference ID/Investigator# 22429, Greenville, South Carolina, 29605, United States|Site Reference ID/Investigator# 22428, Mount Pleasant, South Carolina, 29464, United States|Site Reference ID/Investigator# 25302, Summerville, South Carolina, 29485, United States|Site Reference ID/Investigator# 22812, Dallas, Texas, 75251, United States|Site Reference ID/Investigator# 8536, Edinburg, Texas, 78539, United States|Site Reference ID/Investigator# 22810, Fort Worth, Texas, 76104, United States|Site Reference ID/Investigator# 24742, Houston, Texas, 77005, United States|Site Reference ID/Investigator# 26722, Houston, Texas, 77024, United States|Site Reference ID/Investigator# 8406, Houston, Texas, 77099, United States|Site Reference ID/Investigator# 8232, Lubbock, Texas, 79410, United States|Site Reference ID/Investigator# 22480, San Antonio, Texas, 78224, United States|Site Reference ID/Investigator# 8397, San Antonio, Texas, 78229, United States|Site Reference ID/Investigator# 21804, Ogden, Utah, 84403, United States|Site Reference ID/Investigator# 22423, Salt Lake City, Utah, 84124, United States|Site Reference ID/Investigator# 8413, Gig Harbor, Washington, 98335, United States|Site Reference ID/Investigator# 24402, Carolina, 00983, Puerto Rico|Site Reference ID/Investigator# 22545, Humacao, 00791, Puerto Rico|Site Reference ID/Investigator# 8301, Manati, 00674, Puerto Rico|Site Reference ID/Investigator# 8299, Ponce, 00717-0634, Puerto Rico|Site Reference ID/Investigator# 8418, Ponce, 00717-1322, Puerto Rico|Site Reference ID/Investigator# 8419, Ponce, 00717-2075, Puerto Rico|Site Reference ID/Investigator# 8421, San Juan, 00907, Puerto Rico|Site Reference ID/Investigator# 8300, San Juan, 00909, Puerto Rico|Site Reference ID/Investigator# 8422, San Juan, 00918, Puerto Rico|Site Reference ID/Investigator# 8423, San Juan, 00936-5067, Puerto Rico|Site Reference ID/Investigator# 8420, Toa Baja, 00949, Puerto Rico|Site Reference ID/Investigator# 8298, Yabucoa, 00767, Puerto Rico
URL: https://clinicaltrials.gov/show/NCT00680017

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress