| Trial ID: | L0082 |
| Source ID: | NCT04500665
|
| Associated Drug: |
Colchicine
|
| Title: |
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
|
| Acronym: |
|
| Status: |
RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Chronic Kidney Diseases
|
| Interventions: |
DRUG: Colchicine|DRUG: Placebo
|
| Outcome Measures: |
Primary: Between-group change in left ventricular global longitudinal strain, Assessed using transthoracic echocardiography, 4 weeks | Secondary: Between-group change in left ventricular systolic and diastolic function, Assessed using transthoracic echocardiography, 4 weeks|Between-group change in left ventricular volumes, Assessed using transthoracic echocardiography, 4 weeks|Between-group change in left ventricular size, Assessed using transthoracic echocardiography, 4 weeks|Between-group change in systemic inflammation, Assessed using C-reactive protein, 4 weeks
|
| Sponsor/Collaborators: |
Sponsor: Brigham and Women's Hospital | Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE2
|
| Enrollment: |
20
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2021-11-01
|
| Completion Date: |
2026-11-11
|
| Results First Posted: |
|
| Last Update Posted: |
2024-06-20
|
| Locations: |
Brigham and Women's Hospital, Boston, Massachusetts, 02115, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT04500665
|
