| Outcome Measures: |
Primary: Difference in scores (0-40) for overall palatability of NIMPs, To compare patient-reported overall palatability (composite of taste, texture, smell, and mouthfeel) between Lokelma and Veltassa, and between Lokelma and S/CPS in the United States (US), Tasting visit (day 1) | Secondary: Difference in scores (0-40) for overall palatability of NIMPs, To compare patient-reported overall palatability (composite of taste, texture, smell, and mouthfeel) between Lokelma and Veltassa, and between Lokelma and S/CPS in Canada, Tasting visit (day 1)|Difference in scores (0-40) for overall palatability of NIMPs, To compare patient-reported overall palatability (composite of taste, texture, smell, and mouthfeel) between Lokelma and Veltassa, and between Lokelma and S/CPS in the European Union (EU), Tasting visit (day 1)|Difference in scores for feelings of Appeal (4-36), Engagement (4-36), and Empowerment (4-36) regarding taste overall palatability of NIMPs using the AdSAM emotional response tool, To compare patient-reported emotional response to overall palatability (composite of taste, texture, smell, and mouthfeel) taste between Lokelma and Veltassa, and between Lokelma and S/CPS in the US, Tasting visit (day 1)|Difference in scores for feelings of appeal (4-36), engagement (4-36), and empowerment (4-36) regarding overall palatability of NIMPs using the AdSAM emotional response tool, To compare patient-reported emotional response to overall palatability (composite of taste, texture, smell, and mouthfeel) between Lokelma and Veltassa, and between Lokelma and S/CPS in Canada, Tasting visit (day 1)|Difference in scores for feelings of appeal (4-36), engagement (4-36), and empowerment (4-36) regarding overall palatability of NIMPs using the AdSAM emotional response tool, To compare patient-reported emotional response to overall palatability (composite of taste, texture, smell, and mouthfeel) between Lokelma and Veltassa, and ,between Lokelma and S/CPS in the EU, Tasting visit (day 1)|Scoring of palatability (0-40), Appeal of palatability (4-36), Engagement of palatability (4-36), Empowerment of palatability (4-36), Overall composite emotional strength indicator scores (0-1200), Feelings towards palatability, To describe patient-reported preference for overall palatability (composite of taste, texture, smell, and mouthfeel) (scoring and non-verbal emotional response for how each NIMP made patients feel ofto each NIMP) of 3 currently marketed K+ binders ((of Lokelma, Veltassa, and S/CPS) in the US, Canada, and EU, respectively), Tasting Visit (day 1)|Scoring (0-10), Appeal (9-1), Engagement (9-1), Empowerment (1-9), Overall emotional strength indicator score (0-300), and Feelings towards willingness to take a K+ binder, To describe and compare, based on the overall palatability experience, scoring and emotional response for how willing patients would be to take each K+ binder to help manage their serum potassium (likelihood of adherence) in the US, Canada, and EU, Tasting Visit (day 1)|Overall preference ranking of NIMPs (1, 2, or 3) of Lokelma, Veltassa, and S/CPS • Use of Comparative AdSAM Emotional Strength Index and Emotional TempIndicator scores to derive overall preference, To describe patient-reported preference by ranking the NIMPs, and derived preference based on the emotional strength indexindicator scores in the US, Canada, and EU, Tasting visit (day 1) | Other: See primary and secondary endpoints, Overall palatability scores (0-40) between Lokelma and Veltassa, and between Lokelma and S/CPS will be described and compared for all primary and secondary endpoints for: North America, per individual EU countries (where data permit), and over all countries/regions, Tasting visit (day 1)|See primary and secondary endpoints, Patient preference between Lokelma and Veltassa, and between Lokelma and S/CPS will be described and compared for all primary and secondary endpoints for: North America, per individual EU countries (where data permit), and over all countries/regions., Tasting visit (day 1)|Categories or combinations based on Appeal of each attribute (taste, texture, smell, and mouthfeel), Appeal test score (1-9) for each attribute (taste, texture, smell, and mouthfeel) will be measured using AdSAM questionnaires using published research and analysed using AdSAM methodology and compare between Lokelma and Veltassa, and between Lokelma and S/CPS for the US, Canada, EU, North America, per individual EU countries (where data permit), and over all countries/regions., Tasting visit (day 1)|Categories or combinations based on Engagement of each attribute (taste, texture, smell, and mouthfeel), Engagement test score (1-9) for each attribute (taste, texture, smell, and mouthfeel) will be measured using AdSAM questionnaires team using published research and analysed using AdSAM methodology and compare between Lokelma and Veltassa, and between Lokelma and S/CPS for the US, Canada, EU, North America, per individual EU countries (where data permit), and over all countries/regions, Tasting visit (day 1)|Categories or combinations based on Empowerment of each attribute (taste, texture, smell, and mouthfeel), Empowerment test score (1-9) for each attribute (taste, texture, smell, and mouthfeel) will be measured using AdSAM questionnaires team using published research and analysed using AdSAM methodology and compare between Lokelma and Veltassa, and between Lokelma and S/CPS for the US, Canada, EU, North America, per individual EU countries (where data permit), and over all countries/regions, Tasting visit (day 1)|Scoring (0-10) of taste, texture, smell, and mouthfeel, Scores of individual palatability attributes (taste, texture, smell, and mouthfeel) will be described individually by countries/regions, Tasting visit (day 1)|Determining specific feelings regarding taste, texture, smell, and mouthfeel using the AdSAM emotional response model, Emotional response of individual palatability attributes (taste, texture, smell, and mouthfeel) will be described individually by countries/regions, Tasting visit (day 1)
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| Locations: |
Research Site, Temple Terrace, Florida, 33637, United States|Research Site, West Palm Beach, Florida, 33411, United States|Research Site, Toronto, Ontario, M5G 2C4, Canada|Research Site, Greenfield Park, Quebec, J4V 2H1, Canada|Research Site, Montreal, Quebec, H1T 2M4, Canada|Research Site, Quebec, G1L 3L5, Canada|Research Site, Amiens, 80054, France|Research Site, Boulogne Billancourt Cedex, 92104, France|Research Site, Nice, 06000, France|Research Site, Genova, 16132, Italy|Research Site, Parma, Italy|Research Site, Pavia, 27100, Italy|Research Site, Barcelona, 8035, Spain|Research Site, Córdoba, 14004, Spain|Research Site, La Coruña, 15006, Spain|Research Site, Madrid, 28031, Spain|Research Site, Eskilstuna, 631 88, Sweden|Research Site, Stockholm, 182 88, Sweden
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