| Outcome Measures: |
Primary: Brief Fatigue Inventory (BFI) score, Changes in global fatigue score measured with the 9-item Brief Fatigue Inventory (BFI). The first 3 questions assess fatigue severity, and the remaining 6 questions measure the impact of fatigue on activity, mood, walking, work, relationships, and enjoyment of life. Respondents rate each item on a 0-10 numeric scale, with 0 meaning "no fatigue" and 10 meaning "fatigue as bad as you can imagine." Scores of all 9 items yield global fatigue burden. A lower average global fatigue score indicates milder fatigue and a higher score severe fatigue., Baseline to 17 weeks | Secondary: Handgrip strength test, Change in handgrip strength measured by a dynamometer in lbs, Baseline to 17 weeks|Trail Making Test (TMT), Change in minutes to complete Trail Making Test (TMT) A and B, Baseline to 17 weeks | Other: Dialysate level of amino acids, How is this measured, are there different values for different aa's (if so each one should be reported separately)?, Baseline to 17 weeks|Plasma level of amino acids, How is this measured, are there different values for different aa's (if so each one should be reported separately)?, Baseline to 17 weeks|Blood valine metabolite 3-hydroxyisobutyrate (3-HIB), Change in 3-hydroxyisobutyrate (3-HIB) levels, Baseline to 17 weeks|Blood valine beta-amino-isobutyric acid (BAIBA), Change in beta-amino-isobutyric acid (BAIBA), Baseline to 17 weeks
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