| Trial ID: | L0889 |
| Source ID: | NCT03703154
|
| Associated Drug: |
Envarsus
|
| Title: |
Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Immediate Release Tacrolimus to Slow Release Envarsus
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
End Stage Renal Disease
|
| Interventions: |
DRUG: Envarsus|DRUG: Tacrolimus
|
| Outcome Measures: |
Primary: Change in cognitive function using a battery of neuropsychological tests, Battery aggregate scores include such tests as: Mini Mental Sate Exam, Montreal Cognitive Assessment, Digit Span, Logical Memory, Category Fluency, Trail Making, Digit Symbol, Block Design, Stroop, Buschke Free and Cued Reminding Test., Change from Baseline to Week 12|Change in cerebral blood flow, including brain blood flow response curve to exercise or cerebral reactivity, Change from Baseline to Week 12 |
|
| Sponsor/Collaborators: |
Sponsor: University of Kansas Medical Center | Collaborators: Veloxis Pharmaceuticals
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
30
|
| Study Type: |
OBSERVATIONAL
|
| Study Designs: |
Observational Model: |Time Perspective: p
|
| Start Date: |
2018-10-25
|
| Completion Date: |
2021-03-03
|
| Results First Posted: |
|
| Last Update Posted: |
2021-04-27
|
| Locations: |
University of Kansas Medical Center, Kansas City, Kansas, 66160, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT03703154
|
