Clinical Trial Details
| Trial ID: | L0984 |
| Source ID: | NCT03781726 |
| Associated Drug: | Glecaprevir/Pibrentasvir Treatment |
| Title: | Multi-center Study to Transplant Hepatitis-C Infected Kidneys |
| Acronym: | MYTHIC |
| Status: | COMPLETED |
| Study Results: | YES |
| Results: | https://ClinicalTrials.gov/show/NCT03781726/results |
| Conditions: | Renal Failure Chronic|Hepatitis C |
| Interventions: | DRUG: glecaprevir/pibrentasvir treatment |
| Outcome Measures: | Primary: Number of Participants With Undetectable HCV, HCV RNA \< LLOQ 12 weeks after the last actual dose of G/P, 12 weeks post treatment | Secondary: Percentage of Subjects With On-treatment Virologic Failure, HCV RNA \> LLOQ during G/P treatment, During 8 week treatment course|Percentage of Subjects With Post-treatment Virologic Relapse, HCV RNA \> LLOQ after completion of G/P treatment and prior HCV RNA \< LLOQ while on treatment, During 12 week post treatment follow-up |
| Sponsor/Collaborators: | Sponsor: Raymond Chung | Collaborators: AbbVie|University of Pennsylvania|Johns Hopkins University|University of Cincinnati|Weill Medical College of Cornell University|University of Michigan|Northwestern University |
| Gender: | ALL |
| Age: | ADULT, OLDER_ADULT |
| Phases: | PHASE4 |
| Enrollment: | 30 |
| Study Type: | INTERVENTIONAL |
| Study Designs: | Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION |
| Start Date: | 2019-04-10 |
| Completion Date: | 2021-12-31 |
| Results First Posted: | 2021-05-11 |
| Last Update Posted: | 2022-01-26 |
| Locations: | Northwestern Medicine, Chicago, Illinois, 60611, United States|John Hopkins, Baltimore, Maryland, 21287, United States|Massachusetts General Hospital, Boston, Massachusetts, 02114, United States|University of Michigan, Ann Arbor, Michigan, 48109, United States|Weill Cornell Medical Center, New York, New York, 10065, United States|University of Cincinnati Medical Center, Cincinnati, Ohio, 45219, United States|University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States |
| URL: | https://clinicaltrials.gov/show/NCT03781726 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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