| Trial ID: | L0999 |
| Source ID: | NCT01301027
|
| Associated Drug: |
Pioglitazone
|
| Title: |
Effect of Adipokines in Hemodialysis Patients
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT01301027/results
|
| Conditions: |
End Stage Renal Disease
|
| Interventions: |
DRUG: Pioglitazone|DRUG: Placebo
|
| Outcome Measures: |
Primary: Change in High Molecular Weight Adiponectin (HMW-A) Concentration in Plasma From Baseline to 6 Months, The percent difference in HMW-A concentration geometric mean values from baseline to 6 months was calculated for each arm, Baseline and 6 months|Change in High Sensitivity C-Reactive Protein (hsCRP) Concentration in Plasma From Baseline to 6 Months, The percent difference in hsCRP concentration geometric mean values from baseline to 6 months was calculated for each arm, Baseline and 6 months | Secondary: Change in Tumor Necrosis Factor-α (TNF-α) Concentration in Plasma From Baseline to 6 Months, The percent difference in TNF-α concentration geometric mean values from baseline to 6 months was calculated for each arm, Baseline and 6 months|Change in Interleukin-6 (IL-6) Concentration in Plasma From Baseline to 6 Months, The percent difference in IL-6 concentration geometric mean values from baseline to 6 months was calculated for each arm, Baseline and 6 months
|
| Sponsor/Collaborators: |
Sponsor: University of Utah | Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|University of Colorado, Denver
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
95
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
|
| Start Date: |
2008-05
|
| Completion Date: |
2015-12
|
| Results First Posted: |
2016-10-03
|
| Last Update Posted: |
2016-10-03
|
| Locations: |
University of Colorado, Denver, Colorado, 80262, United States|University of Utah, Salt Lake City, Utah, 84112, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT01301027
|
