Bioactive Compounds
Drug-like bioactive compounds for CKD-related targets (i.e., therapeutic targets in CKDdb) are extracted from ChEMBL. Detailed information and structure for each compound are provided, along with knowledge graphs linked with related therapeutic targets.
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Uncharacterized aarF domain-containing protein kinase 482 records.
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000250 | CHEMBL10 | Small molecule | SB-203580 | 377.44 | C21H16FN3OS | NEUTRAL | Details |
| B000273 | CHEMBL440084 | Small molecule | SB-431542 | 384.4 | C22H16N4O3 | NEUTRAL | Details |
| B013048 | CHEMBL535 | Small molecule | SUNITINIB | 398.48 | C22H27FN4O2 | BASE | Details |
| B014221 | CHEMBL14762 | Small molecule | SELICICLIB | 354.46 | C19H26N6O | NEUTRAL | Details |
| B014366 | CHEMBL428690 | Small molecule | ALVOCIDIB | 401.85 | C21H20ClNO5 | NEUTRAL | Details |
| B014785 | CHEMBL553 | Small molecule | ERLOTINIB | 393.44 | C22H23N3O4 | NEUTRAL | Details |
| B014805 | CHEMBL554 | Small molecule | LAPATINIB | 581.07 | C29H26ClFN4O4S | NEUTRAL | Details |
| B019081 | CHEMBL278041 | Small molecule | SB-202190 | 331.35 | C20H14FN3O | NEUTRAL | Details |
| B033576 | CHEMBL24828 | Small molecule | VANDETANIB | 475.36 | C22H24BrFN4O2 | BASE | Details |
| B041764 | CHEMBL31965 | Small molecule | CANERTINIB | 485.95 | C24H25ClFN5O3 | NEUTRAL | Details |
| B062111 | CHEMBL288441 | Small molecule | BOSUTINIB | 530.46 | C26H29Cl2N5O3 | NEUTRAL | Details |
| B071663 | CHEMBL296468 | Small molecule | BMS-387032 | 380.54 | C17H24N4O2S2 | BASE | Details |
| B083217 | CHEMBL300138 | Small molecule | ENZASTAURIN | 515.62 | C32H29N5O2 | NEUTRAL | Details |
| B088232 | CHEMBL939 | Small molecule | GEFITINIB | 446.91 | C22H24ClFN4O3 | NEUTRAL | Details |
| B088797 | CHEMBL941 | Small molecule | IMATINIB | 493.62 | C29H31N7O | NEUTRAL | Details |
| B144959 | CHEMBL91829 | Small molecule | RUBOXISTAURIN | 468.56 | C28H28N4O3 | BASE | Details |
| B165012 | CHEMBL101253 | Small molecule | VATALANIB | 346.82 | C20H15ClN4 | NEUTRAL | Details |
| B167995 | CHEMBL103667 | Small molecule | DORAMAPIMOD | 527.67 | C31H37N5O3 | NEUTRAL | Details |
| B169054 | CHEMBL105442 | Small molecule | CI-1040 | 478.66 | C17H14ClF2IN2O2 | NEUTRAL | Details |
| B193962 | CHEMBL119385 | Small molecule | NEFLAMAPIMOD | 436.27 | C19H9Cl2F2N3OS | Details | |
| B205165 | CHEMBL124660 | Small molecule | TANDUTINIB | 562.72 | C31H42N6O4 | BASE | Details |
| B276734 | CHEMBL1336 | Small molecule | SORAFENIB | 464.83 | C21H16ClF3N4O3 | NEUTRAL | Details |
| B299120 | CHEMBL180022 | Small molecule | NERATINIB | 557.05 | C30H29ClN6O3 | BASE | Details |
| B317507 | CHEMBL191003 | Small molecule | JNJ-7706621 | 394.36 | C15H12F2N6O3S | NEUTRAL | Details |
| B343041 | CHEMBL377300 | Small molecule | BRIVANIB | 370.38 | C19H19FN4O3 | NEUTRAL | Details |
| B350635 | CHEMBL379218 | Small molecule | 358.45 | C22H22N4O | BASE | Details | |
| B359195 | CHEMBL386051 | Small molecule | 443.36 | C21H16Cl2N4OS | NEUTRAL | Details | |
| B361203 | CHEMBL384304 | Small molecule | RG-547 | 441.46 | C18H21F2N5O4S | NEUTRAL | Details |
| B361469 | CHEMBL1421 | Small molecule | DASATINIB | 488.02 | C22H26ClN7O2S | NEUTRAL | Details |
| B363083 | CHEMBL215152 | Small molecule | AZD-1152-HQPA | 507.57 | C26H30FN7O3 | BASE | Details |
| B367860 | CHEMBL221959 | Small molecule | TOFACITINIB | 312.38 | C16H20N6O | NEUTRAL | Details |
| B371147 | CHEMBL223360 | Small molecule | LINIFANIB | 375.41 | C21H18FN5O | NEUTRAL | Details |
| B373381 | CHEMBL388978 | Small molecule | STAUROSPORINE | 466.54 | C28H26N4O3 | BASE | Details |
| B387990 | CHEMBL230011 | Small molecule | TG100-115 | 346.35 | C18H14N6O2 | NEUTRAL | Details |
| B413815 | CHEMBL249097 | Small molecule | 335.37 | C18H17N5O2 | NEUTRAL | Details | |
| B413905 | CHEMBL249697 | Small molecule | BMS-345541 | 255.32 | C14H17N5 | BASE | Details |
| B426660 | CHEMBL255863 | Small molecule | NILOTINIB | 529.53 | C28H22F3N7O | NEUTRAL | Details |
| B428508 | CHEMBL259084 | Small molecule | MLN-8054 | 476.87 | C25H15ClF2N4O2 | ACID | Details |
| B430664 | CHEMBL261849 | Small molecule | GW632580X | 366.42 | C20H22N4O3 | NEUTRAL | Details |
| B436277 | CHEMBL572878 | Small molecule | TOZASERTIB | 464.6 | C23H28N8OS | NEUTRAL | Details |
| B447415 | CHEMBL450786 | Small molecule | PHA-665752 | 641.62 | C32H34Cl2N4O4S | BASE | Details |
| B447450 | CHEMBL509032 | Small molecule | TAE-684 | 614.22 | C30H40ClN7O3S | NEUTRAL | Details |
| B456867 | CHEMBL491473 | Small molecule | CEDIRANIB | 450.51 | C25H27FN4O3 | BASE | Details |
| B460144 | CHEMBL475251 | Small molecule | R-406 | 470.46 | C22H23FN6O5 | NEUTRAL | Details |
| B469313 | CHEMBL494089 | Small molecule | GSK-690693 | 425.49 | C21H27N7O3 | BASE | Details |
| B470511 | CHEMBL521851 | Small molecule | PICTILISIB | 513.65 | C23H27N7O3S2 | NEUTRAL | Details |
| B489525 | CHEMBL477772 | Small molecule | PAZOPANIB | 437.53 | C21H23N7O2S | NEUTRAL | Details |
| B490644 | CHEMBL513909 | Small molecule | BI-2536 | 521.67 | C28H39N7O3 | BASE | Details |
| B494834 | CHEMBL522892 | Small molecule | DOVITINIB | 392.44 | C21H21FN6O | NEUTRAL | Details |
| B495436 | CHEMBL464552 | Small molecule | 532.58 | C27H29FN8O3 | NEUTRAL | Details | |
| B508707 | CHEMBL483321 | Small molecule | CP-724714 | 469.55 | C27H27N5O3 | NEUTRAL | Details |
| B510783 | CHEMBL525191 | Small molecule | 334.38 | C19H18N4O2 | NEUTRAL | Details | |
| B511261 | CHEMBL445813 | Small molecule | AT-7519 | 382.25 | C16H17Cl2N5O2 | BASE | Details |
| B522730 | CHEMBL502835 | Small molecule | NINTEDANIB | 539.64 | C31H33N5O4 | NEUTRAL | Details |
| B568338 | CHEMBL572881 | Small molecule | MOTESANIB | 373.46 | C22H23N5O | NEUTRAL | Details |
| B568339 | CHEMBL574738 | Small molecule | AST-487 | 529.57 | C26H30F3N7O2 | NEUTRAL | Details |
| B568340 | CHEMBL558752 | Small molecule | RAF-265 | 518.42 | C24H16F6N6O | NEUTRAL | Details |
| B568342 | CHEMBL573339 | Small molecule | PI-103 | 348.36 | C19H16N4O3 | NEUTRAL | Details |
| B573133 | CHEMBL576982 | Small molecule | QUIZARTINIB | 560.68 | C29H32N6O4S | NEUTRAL | Details |
| B597145 | CHEMBL603469 | Small molecule | LESTAURTINIB | 439.47 | C26H21N3O4 | NEUTRAL | Details |
| B600132 | CHEMBL608154 | Small molecule | 366.81 | C19H15ClN4O2 | NEUTRAL | Details | |
| B602271 | CHEMBL601719 | Small molecule | CRIZOTINIB | 450.35 | C21H22Cl2FN5O | BASE | Details |
| B604615 | CHEMBL607707 | Small molecule | PELITINIB | 467.93 | C24H23ClFN5O2 | BASE | Details |
| B608601 | CHEMBL608533 | Small molecule | MIDOSTAURIN | 570.65 | C35H30N4O4 | NEUTRAL | Details |
| B650126 | CHEMBL1173655 | Small molecule | AFATINIB | 485.95 | C24H25ClFN5O3 | BASE | Details |
| B692370 | CHEMBL1230020 | Small molecule | PLX-4720 | 413.83 | C17H14ClF2N3O3S | NEUTRAL | Details |
| B692959 | CHEMBL1230609 | Small molecule | FORETINIB | 632.66 | C34H34F2N4O6 | NEUTRAL | Details |
| B698457 | CHEMBL1236107 | Small molecule | SGX-523 | 359.42 | C18H13N7S | NEUTRAL | Details |
| B699914 | CHEMBL1240703 | Small molecule | CGP-52421 | 586.65 | C35H30N4O5 | NEUTRAL | Details |
| B700895 | CHEMBL1241674 | Small molecule | 308.35 | C16H16N6O | NEUTRAL | Details | |
| B714243 | CHEMBL1287853 | Small molecule | FEDRATINIB | 524.69 | C27H36N6O3S | BASE | Details |
| B716337 | CHEMBL1289926 | Small molecule | AXITINIB | 386.48 | C22H18N4OS | NEUTRAL | Details |
| B1037712 | CHEMBL1614701 | Small molecule | SELUMETINIB | 457.69 | C17H15BrClFN4O3 | NEUTRAL | Details |
| B1102616 | CHEMBL1721885 | Small molecule | SU-014813 | 442.49 | C23H27FN4O4 | NEUTRAL | Details |
| B1153572 | CHEMBL1789941 | Small molecule | RUXOLITINIB | 306.37 | C17H18N6 | NEUTRAL | Details |
| B1248752 | CHEMBL1908391 | Small molecule | MASITINIB | 498.66 | C28H30N6OS | NEUTRAL | Details |
| B1248755 | CHEMBL1908394 | Small molecule | GSK-461364 | 543.62 | C27H28F3N5O2S | NEUTRAL | Details |
| B1248756 | CHEMBL1908395 | Small molecule | 460.58 | C26H33ClN6O2 | NEUTRAL | Details | |
| B1248757 | CHEMBL1908396 | Small molecule | 480.55 | C24H24N4O5S | NEUTRAL | Details | |
| B1248758 | CHEMBL1908397 | Small molecule | KW-2449 | 332.41 | C20H20N4O | NEUTRAL | Details |
| B1445393 | CHEMBL2205766 | Small molecule | 346.42 | C15H18N6O2S | NEUTRAL | Details | |
| B1580744 | CHEMBL2425628 | Small molecule | 555.7 | C28H37N5O5S | NEUTRAL | Details |