Therapeutic Target Details
| Target ID: | T30 |
| Target Name: | TP53-regulating kinase |
| Synonyms: | C20orf64; PRPK; Synonyms=C20orf64; EKC/KEOPS complex subunit TP53RK; Atypical serine/threonine protein kinase TP53RK; Nori-2; TP53-regulating kinase; p53-related protein kinase; 3.6.-.-; 2.7.11.1 |
| GENE: | TP53RK |
| Action: | |
| Class: | Target is a single protein chain |
| UniProtKB ID: | Q96S44 |
| Entry Name: | TP53RK_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000923 | CHEMBL413 | Small molecule | SIROLIMUS | 914.19 | C51H79NO13 | NEUTRAL | Details |
| B012922 | CHEMBL274654 | Small molecule | ORANTINIB | 310.35 | C18H18N2O3 | ACID | Details |
| B013048 | CHEMBL535 | Small molecule | SUNITINIB | 398.48 | C22H27FN4O2 | BASE | Details |
| B014221 | CHEMBL14762 | Small molecule | SELICICLIB | 354.46 | C19H26N6O | NEUTRAL | Details |
| B014366 | CHEMBL428690 | Small molecule | ALVOCIDIB | 401.85 | C21H20ClNO5 | NEUTRAL | Details |
| B014785 | CHEMBL553 | Small molecule | ERLOTINIB | 393.44 | C22H23N3O4 | NEUTRAL | Details |
| B014805 | CHEMBL554 | Small molecule | LAPATINIB | 581.07 | C29H26ClFN4O4S | NEUTRAL | Details |
| B030847 | CHEMBL283120 | Small molecule | AXL-1717 | 414.41 | C22H22O8 | NEUTRAL | Details |
| B033576 | CHEMBL24828 | Small molecule | VANDETANIB | 475.36 | C22H24BrFN4O2 | BASE | Details |
| B035352 | CHEMBL281948 | Small molecule | K-252A | 467.48 | C27H21N3O5 | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
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