Bioactive Compound Details
| Compound ID: | B030847 |
| Source ID: | CHEMBL283120 |
| Source Type: | Small molecule |
| Compound Name: | AXL-1717 |
| Synonyms: | AXL-1717|Axl-1717|Axl1717|NSC-36407|Picropodophyllin|Picropodophyllotoxin|Podophyllotoxin picropodophyllin |
| Molecular Formula: | C22H22O8 |
| SMILES: | COc1cc([C@@H]2c3cc4c(cc3[C@H](O)[C@H]3COC(=O)[C@@H]23)OCO4)cc(OC)c1OC |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |