Therapeutic Targets
Therapeutic targets for CKD are manually extracted from research articles. For each target, reference researches are provided, and target details are derived from UniProt. Related drugs and repositioning candidates in CKDdb are presented with knowledge graphs.
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52 records.
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T41 | Solute carrier family 13 member 5 | SLC13A5 | Target is a single protein chain | Q86YT5 | SLC13A5_HUMAN | Details | |
| T42 | Collagen alpha-4(IV) chain | COL4A4 | INHIBITOR | Target is a single protein chain | P53420 | COL4A4_HUMAN | Details |
| T43 | Receptor-type tyrosine-protein phosphatase O | PTPRO | Hydrolase | Q16827 | PTPRO_HUMAN | Details | |
| T44 | Low-density lipoprotein receptor-related protein 5 | LRP5 | Target is a single protein chain | O75197 | LRP5_HUMAN | Details | |
| T45 | Insulin receptor substrate 1 | IRS1 | Target is a single protein chain | P35568 | IRS1_HUMAN | Details | |
| T46 | Endonuclease 8-like 1 | NEIL1 | Hydrolase | Q96FI4 | NEIL1_HUMAN | Details | |
| T47 | Sialin | SLC17A5 | Target is a single protein chain | Q9NRA2 | SLC17A5_HUMAN | Details | |
| T48 | Wilms tumor protein | WT1 | VACCINE ANTIGEN | Target is a single protein chain | P19544 | WT1_HUMAN | Details |
| T49 | Apolipoprotein L1 | APOL1 | Target is a single protein chain | O14791 | APOL1_HUMAN | Details | |
| T50 | Interferon-induced helicase C domain-containing protein 1 | IFIH1 | Hydrolase | Q9BYX4 | IFIH1_HUMAN | Details | |
| T51 | Paired box protein Pax-2 | PAX2 | Target is a single protein chain | Q02962 | PAX2_HUMAN | Details | |
| T52 | CD2-associated protein | CD2AP | Target is a single protein chain | Q9Y5K6 | CD2AP_HUMAN | Details |