| Trial ID: | L2615 |
| Source ID: | NCT05194592
|
| Associated Drug: |
Dapagliflozin
|
| Title: |
Comparison of the Effects of Dapagliflozin and Gemigliptin on Ketone Metabolism and Cardiac Remodeling in Type 2 Diabetes
|
| Acronym: |
|
| Status: |
RECRUITING
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type2 Diabetes|Remodeling, Ventricular
|
| Interventions: |
DRUG: Dapagliflozin|DRUG: Gemigliptin
|
| Outcome Measures: |
Primary: Change (%) in acetoacetate, total ketone, beta-hydroxybutyric acid, The change of acetoacetate, total ketone, beta-hydroxybutyric acid from baseline to 6 months follow-up, 6 months|Change (%) in LV mass index, The change of LV mass index from baseline to 6 months follow-up, 6 months | Secondary: Change (%) in LV ejection global longitudinal strain, The change of LV mass ejection global longitudinal strain from baseline to 6 months follow-up, 6 months|Change (%) in mean 24hr ambulatory systolic and diastolic blood pressure, The change of mean 24hr ambulatory systolic and diastolic blood pressurefrom baseline to 6 months follow-up, 6 months
|
| Sponsor/Collaborators: |
Sponsor: Wonju Severance Christian Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
122
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2022-01-07
|
| Completion Date: |
2025-06-30
|
| Results First Posted: |
|
| Last Update Posted: |
2023-08-01
|
| Locations: |
Yonsei University Wonju College of Medicine, Wonju, Gangwondo, 26426, Korea, Republic of
|
| URL: |
https://clinicaltrials.gov/show/NCT05194592
|
