| Trial ID: | L2945 |
| Source ID: | NCT05335629
|
| Associated Drug: |
Dapagliflozin 10mg Tab
|
| Title: |
Evaluation of the Effect of SGLT-2 Inhibitors on Cardiac Remodeling in Post Myocardial Infarction Patients
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Myocardial Infarction|Diabetes Mellitus, Type 2|Myocardial Remodeling, Ventricular
|
| Interventions: |
DRUG: Dapagliflozin 10Mg Tab
|
| Outcome Measures: |
Primary: Effect on ST2 (suppression of tumerogenicity 2) level in the acute phase after myocardial infarction, patients will be followed up for the whole period of the study and blood sample will be drawn at baseline and at study end to track changes in the level of ST2 (suppression of tumerogenicity 2) which is a cardiac remodeling biomarker using ELISA technique, 4 weeks | Secondary: Echocardiographic changes due to intervention, patients will have their echocardiography and ejection fraction will be compared at baseline and at the end of the study to track any changes that may be caused by intervention, 4 weeks
|
| Sponsor/Collaborators: |
Sponsor: Ain Shams University
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
|
| Enrollment: |
54
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
|
| Start Date: |
2022-06-01
|
| Completion Date: |
2023-10-01
|
| Results First Posted: |
|
| Last Update Posted: |
2024-02-01
|
| Locations: |
Ain shams university hospitals, Cairo, Egypt
|
| URL: |
https://clinicaltrials.gov/show/NCT05335629
|
