| Trial ID: | L4019 |
| Source ID: | NCT02516150
|
| Associated Drug: |
Ethanol
|
| Title: |
Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT02516150/results
|
| Conditions: |
Type 1 Diabetes Mellitus
|
| Interventions: |
DRUG: Ethanol|DRUG: Glucagon
|
| Outcome Measures: |
Primary: AOCGIR (Area Over the Curve for Glucose Infusion Rate), Area over the curve for the glucose infusion rate in the hour following a subcutaneous glucagon dose with a blood alcohol content of 0 vs 0.1%, 1 Day Visit (approximately 8 to 11 hours) | Secondary: Maximum Change in GIR (Glucose Infusion Rate) From Baseline, This outcome is measuring the maximum change in the glucose infusion rate from the GIR at the time of the injection through the 90 minutes after the glucagon injection in the presence and absence of ethanol. The glucose infusion rate is adjusted up to every two minutes throughout the clamp, and for 90 minutes total after the glucagon injection., 1 Day Visit (approximately 8 to 11 hours)
|
| Sponsor/Collaborators: |
Sponsor: Massachusetts General Hospital
|
| Gender: |
ALL
|
| Age: |
ADULT, OLDER_ADULT
|
| Phases: |
PHASE4
|
| Enrollment: |
26
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
|
| Start Date: |
2016-03
|
| Completion Date: |
2017-06
|
| Results First Posted: |
2017-08-31
|
| Last Update Posted: |
2017-08-31
|
| Locations: |
Massachusetts General Hospital Diabetes Research Center, Boston, Massachusetts, 02114, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT02516150
|
