Outcome Measures: |
Primary: Urinary Phthalates concentration, Exposure to phthalates assessed through urinary concentration of phthalates metabolites spot and 24-hours, Changes between baseline and 1 month|Urinary Phthalates concentration, Exposure to phthalates assessed through urinary excretion spot and 24-hours, Changes between baseline and 3 month | Secondary: Fasting glucose, Fasting glucose measured in a fasting morning blood sample, 1 and 3 months|Glycated Haemoglobin, HbA1c in a fasting measured in a morning blood sample, 1 and 3 months|Renal function, Using creatinine measured in a fasting morning blood sample and estimated by eGFR (calculated with the CDK-EPI formula), 1 and 3 months|Macrovascular events, Number of participants with MACE events (Stroke, Acute Myocardial Infarction, Unstable Angina, Revascularization), 1 and 3 months|Albumin excretion, Measured by urinary albumin/creatinine ratio, 1 and 3 months
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