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Clinical Trial Details

Trial ID: L4744
Source ID: NCT04195243
Associated Drug: Dapagliflozin Pill
Title: Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Acronym:
Status: UNKNOWN
Study Results: NO
Results:
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin Pill|DRUG: Empagliflozin Pill|DRUG: Placebo pill
Outcome Measures: Primary: Flow Mediated Dilation, Change from baseline Flow mediated dilation at 7 days. Using a high-resolution UNEX EF38G ultrasound®, in a room at 22°C, with the patient lying supine, and the right arm extended, 7 days | Secondary: Fasting plasma glucose, Before and after intervention, using the BioSystems® Glucose Oxidase / Peroxidase kit; in an automated clinical chemistry analysis equipment brand XL-100Erba, 7 days|Total cholesterol, Before and after intervention, using the BioSystems® Glucose Oxidase / Peroxidase kit., 7 days|Triglycerides, Before and after intervention, using the BioSystems® Glycerol phosphate Oxidase / Peroxidase kit., 7 days|High-density lipoprotein cholesterol, Before and after intervention, using the BioSystems® Direct / Detergent HDL kit, 7 days|Low-density lipoprotein cholesterol, Before and after intervention using the BioSystems® Cholesterol Oxidase / Peroxidase kit, 7 days|Creatinine, Before and after intervention the BioSystems® kit Modified Jaffe's no deproteinization, 7 days|Blood pressure, Before and after intervention using an OMRON calibrated electronic digital sphygmomanometer model HEM 907 XL will be used. The patient will remain seated in a chair resting his back on the backrest, with a minimum rest of 5 minutes, The average of 3 measurements such as BP will be taken, 7 days
Sponsor/Collaborators: Sponsor: Centro Universitario de Ciencias de la Salud, Mexico
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE3
Enrollment: 24
Study Type: INTERVENTIONAL
Study Designs: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Start Date: 2019-12-02
Completion Date: 2020-12-30
Results First Posted:
Last Update Posted: 2019-12-11
Locations: Institute of Experimental and Clinical Therapeutics (INTEC), CUCS, University of Guadalajara, Guadalajara, Jalisco, 44340, Mexico
URL: https://clinicaltrials.gov/show/NCT04195243