Outcome Measures: |
Primary: renal morphology - fibroblasts, integrity of peritubular fibroblasts (PDGFRα) assessed from the routine one year follow up biopsy of the renal transplant, 3 months after randomization|renal morphology - inflammation, markers of inflammation (example CD3, CD68, CD163) in the interstitium from the routine one year follow up biopsy of the renal transplant, 3 months after randomization|renal morphology - oxidative stress, markers of oxidative stress (Nox1, 8-OHdG) in the interstitium assessed from the routine one year follow up biopsy of the renal transplant, 3 months after randomization | Secondary: mRNA Expression profile of transcripts, mRNA Expression profile of transcripts relevant in renal transplantation using the Human Organ Transplant Panel of NanoString including 770 genes., 3 months after randomization|renal perfusion, renal perfusion of the renal transplant measured by ASL-MRI, 3 months after randomization|central (aortic) systolic pressurepulse pressure, central (aortic) systolic pressure and pulse pressure, 3 months after randomization|pulse pressure, pulse pressure, 3 months after randomization
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