| Trial ID: | L3541 |
| Source ID: | NCT05210504
|
| Associated Drug: |
L-Lysine
|
| Title: |
Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
|
| Acronym: |
|
| Status: |
COMPLETED
|
| Study Results: |
YES
|
| Results: |
https://ClinicalTrials.gov/show/NCT05210504/results
|
| Conditions: |
Diabetes Mellitus, Type 2
|
| Interventions: |
DRUG: L-Lysine|DRUG: Normal Saline
|
| Outcome Measures: |
Primary: Change in Level of 13C 2-AAA in Plasma, Alpha aminoadipic acid (2-AAA) concentration determined through mass spectrometry, quantified to standard. The change was calculated as the area under the curve from baseline to 6 hours post-lysine administration of isotope labeled 2-AAA., Baseline to 6 Hours post-lysine administration|Change in Level of 2-AAA in Urine, Alpha aminoadipic acid (2-AAA) concentration determined through mass spectrometry, quantified to standard. The change was calculated as the total amount of 13C 2-AAA in micromoles excreted from Baseline to 6 hours., Baseline to 6 Hours post-lysine administration |
|
| Sponsor/Collaborators: |
Sponsor: Vanderbilt University Medical Center
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
PHASE1
|
| Enrollment: |
23
|
| Study Type: |
INTERVENTIONAL
|
| Study Designs: |
Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
|
| Start Date: |
2022-03-09
|
| Completion Date: |
2023-01-27
|
| Results First Posted: |
2024-06-05
|
| Last Update Posted: |
2024-06-05
|
| Locations: |
Vanderbilt University Medical Center, Nashville, Tennessee, 37212, United States
|
| URL: |
https://clinicaltrials.gov/show/NCT05210504
|
