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Clinical Trial Details

Trial ID: L4035
Source ID: NCT05713396
Associated Drug: Quinapril
Title: Diabetic Autonomic Neuropathy and Left Ventricular Function
Acronym: DANEL
Status: COMPLETED
Study Results: NO
Results:
Conditions: Diabetes Mellitus
Interventions: DRUG: Quinapril|DRUG: Losartan|DRUG: Quinapril + Losartan
Outcome Measures: Primary: MCR, Mean Circular Resultant, 4 years|AV, Atrial contribution to ventricular filling, 4 years | Secondary: E/I Index, Expiration/Inspiration Index, 4 years|SD, Standard Deviation, 4 years|Valsalva Index, Valsalva Maneuver, 4 years|30:15 Index, Variation of R-R interval during postural change, 4 years|Postural hypotension, Variation of systolic blood pressure during postural change (standing), 4 years|EF, Left ventricular ejection fraction, 4 years|PER, Peak emptying rate, 4 years|PFR, Peak filling rate Peak filling rate, 4 years|1/3 FF, Filling fraction during the first third of the diastole, 4 years|TPF/FT, Time to peak filling time/filling time, 4 years
Sponsor/Collaborators: Sponsor: AHEPA University Hospital
Gender: ALL
Age: ADULT, OLDER_ADULT
Phases: PHASE4
Enrollment: 59
Study Type: INTERVENTIONAL
Study Designs: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Start Date: 2017-01-01
Completion Date: 2022-06-01
Results First Posted:
Last Update Posted: 2023-02-06
Locations: Diabetes Center, 1st Propeudetic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, "AHEPA'' Hospital, Thessaloníki, 54636, Greece
URL: https://clinicaltrials.gov/show/NCT05713396

Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D255 Quinapril small molecule DB00881 Details
D192 Losartan small molecule DB00678 Details