| Outcome Measures: |
Primary: Waist Circumference at Week 12., The waist circumference is going to be evaluated at week 12 with a flexible tape with standardized techniques., Week 12|Triglycerides Levels at Week 12., The triglycerides levels are going to be evaluated at week 12 with enzymatic-colorimetric techniques., Week 12|High Density Lipoprotein (c-HDL) Levels at Week 12., The c-HDL levels are going to be evaluated at week 12 with enzymatic/colorimetric techniques., Week 12|Glucose Levels at Minute 0 at Week 12., The fasting glucose (0') levels are going to be evaluated at week 12 with enzymatic/colorimetric techniques., Week 12|Systolic Blood Pressure at Week 12., The systolic blood pressure is going to be evaluated at week 12 with a digital sphygmomanometer., Week 12|Diastolic Blood Pressure at Week 12., The diastolic blood pressure is going to be evaluated at week 12 with a digital sphygmomanometer., Week 12|Insulinogenic Index (Total Insulin Secretion) at Week 12., The insulinogenic index is a ratio that relates enhancement of circulating insulin to the magnitude of the corresponding glycemic stimulus. Total insulin secretion was calculated with the insulinogenic index (ΔAUC insulin/ΔAUC glucose), the entered values reflect the total insulin secretion at week 12., Week 12|Stumvoll Index (First Phase of Insulin Secretion) at Week 12., Human studies support the critical physiologic role of the first-phase of insulin secretion in the maintenance of postmeal glucose homeostasis. First phase of insulin secretion was estimated using the Stumvoll index (1283+ 1.829 x insulin 30' - 138.7 x glucose 30' + 3.772 x insulin 0'), the entered values reflect the frst phase of insulin secretion at week 12., Week 12|Matsuda Index (Total Insulin Sensitivity) at Week 12., Matsuda Index value is used to indicate insulin resistance on diabetes. Insulin sensitivity was calculated with Matsuda index \[10,000 / √glucose 0' x insulin 0') (mean glucose oral glucose tolerance test (OGTT) x mean insulin OGTT)\]. The entered values reflect the insulin sensitivity at week 12., Week 12 | Secondary: Body Weight at Week 12., The weight it's going to be measured at week 12 with a bioimpedance balance., Week 12|Body Mass Index at Week 12, The Body Mass index it's going to be calculated at week 12 with the Quetelet index., Week 12|Fat Mass at Week 12., The fat mass is going to be evaluated at week 12 through bioimpedance., Week 12|Total Cholesterol at Week 12, The total cholesterol will be estimated by standardized techniques at week 12., Week 12|Low Density Lipoproteins (c-LDL) at Week 12, The c-LDL levels are going to be measured at week 12 with standardized techniques., Week 12|Alanine Aminotransferase (ALT) at Week 12., The ALT hepatic transaminase levels are going to be measured at week 12 with standardized techniques., Week 12.|Aspartate Aminotransferase (AST) at Week 12., The hepatic transaminase AST will be evaluated with standardized methods at week 12, Week 12|Creatinine at Week 12., The creatinine levels are going to be measured at week 12 with standardized techniques., Week 12.|Uric Acid at Week 12., The uric acid levels are going to be measured at week 12 with standardized techniques., Week 12.|AUC of Glucose at Week 12., The AUC of glucose will be calculated from the glucose values obtained from the minuted oral glucose tolerance curve at week 12, Week 12|AUC of Insulin at Week 12., The AUC will be calculated from the insulin values obtained from the minuted oral glucose tolerance curve at week 12, Week 12|Glucose at Minute 30 at Week 12., The glucose at minute 30 is going to be evaluated at week 12 during a minuted oral glucose tolerance curve, Week 12|Glucose at Minute 60 at Week 12., The glucose at minute 60 is going to be evaluated at week 12 during a minuted oral glucose tolerance curve, Week 12|Glucose at Minute 90 at Week 12., The glucose at minute 90 is going to be evaluated at week 12 during a minuted oral glucose tolerance curve, Week 12|Glucose at Minute 120 at Week 12., The glucose at minute 120 is going to be evaluated at week 12 during a minuted oral glucose tolerance curve, Week 12
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