| Trial ID: | L7356 |
| Source ID: | NCT01097551
|
| Associated Drug: |
Trinitrin
|
| Title: |
Endothelial Dysfunction and Diabetes
|
| Acronym: |
DENDI
|
| Status: |
COMPLETED
|
| Study Results: |
NO
|
| Results: |
|
| Conditions: |
Type 1 Diabetes Mellitus
|
| Interventions: |
DRUG: Trinitrin|DRUG: Neosynephrine 10% collyrium|DRUG: Iontophoresis with acetylcholine delivery|DEVICE: Dynamic Vessel Analyzer
|
| Outcome Measures: |
Primary: Evaluation of the presence of a retinal endothelial dysfunction in patients with type 1 diabetes mellitus with Dynamic vessel analyser(assessment study visit), up to 4 months | Secondary: Presence of a peripheral endothelial dysfunction, up to 4 months|Correlation between retinal and peripheral endothelial dysfunction (assessment study visit), up to 4 months|Serum concentration of: CRP, ICAM-1, VCAM-1, VEGF, angiopoietin 2 and endostatin., up to 4 months
|
| Sponsor/Collaborators: |
Sponsor: Assistance Publique - Hôpitaux de Paris
|
| Gender: |
ALL
|
| Age: |
ADULT
|
| Phases: |
|
| Enrollment: |
38
|
| Study Type: |
OBSERVATIONAL
|
| Study Designs: |
Observational Model: |Time Perspective: p
|
| Start Date: |
2011-01
|
| Completion Date: |
2011-07
|
| Results First Posted: |
|
| Last Update Posted: |
2012-07-03
|
| Locations: |
Hôpital LARIBOISIERE Service d'Ophtalmologie, Paris, 75010, France
|
| URL: |
https://clinicaltrials.gov/show/NCT01097551
|
