Bioactive Compound Details
| Compound ID: | B1297331 |
| Source ID: | CHEMBL1976040 |
| Source Type: | Small molecule |
| Compound Name: | ADAVOSERTIB |
| Synonyms: | Adavosertib|Adavosertib|Adavosertib|AZD 1775|Azd-1775|AZD-1775|AZD1775|MK-1775|MK1775 |
| Molecular Formula: | C27H32N8O2 |
| SMILES: | C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |