Bioactive Compound Details
| Compound ID: | B1383172 |
| Source ID: | CHEMBL2110732 |
| Source Type: | Small molecule |
| Compound Name: | DACOMITINIB ANHYDROUS |
| Synonyms: | Dacomitinib anhydrous|Dacomitinib anhydrous|Pf-00299804 |
| Molecular Formula: | C24H25ClFN5O2 |
| SMILES: | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCCCC1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |